Evidence map›Paper›PMID 29500267›Full record

ArticleApplied and environmental microbiology2018

Promoter Engineering Reveals the Importance of Heptameric Direct Repeats for DNA Binding by Streptomyces Antibiotic Regulatory Protein-Large ATP-Binding Regulator of the LuxR Family (SARP-LAL) Regulators in Streptomyces natalensis.

Eva G Barreales, Cláudia M Vicente, Antonio de Pedro, Javier Santos-Aberturas, Jesús F Aparicio

Open access · hybridAbstract read
In one paragraph

Article in Applied and environmental microbiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 23 citations in OpenAlex.

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  7. Recent Advances in Silent Gene Cluster Activation inFrontiers in bioengineering and biotechnology · 2021
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Eva G BarrealesArea of Microbiology, Faculty of Biology, University of León, León, Spain.
Cláudia M VicenteArea of Microbiology, Faculty of Biology, University of León, León, Spain.
Antonio de PedroArea of Microbiology, Faculty of Biology, University of León, León, Spain.
Javier Santos-AberturasArea of Microbiology, Faculty of Biology, University of León, León, Spain.
Jesús F AparicioArea of Microbiology, Faculty of Biology, University of León, León, Spain jesus.aparicio@unileon.es.ORCID 0000-0003-4242-4701
Universidad de León · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The biosynthesis of small-size polyene macrolides is ultimately controlled by a couple of transcriptional regulators that act in a hierarchical way. A

Indexed as

Gene Expression Regulation, BacterialGenetic EngineeringPromoter Regions, GeneticAntifungal AgentsBacterial ProteinsGenes, RegulatorNatamycinOperator Regions, GeneticPolyenesProtein BindingRepetitive Sequences, Nucleic AcidRepressor ProteinsStreptomycesTrans-ActivatorsTranscription FactorsAntifungal AgentsBacterial ProteinsLuxR autoinducer binding proteinsNatamycinPolyenesRepressor ProteinsTrans-ActivatorsTranscription Factorsantifungal agentgene regulationLuxRPAS domainpolyene macrolideSARP-LAL regulatorStreptomyces

Identifiers

PMID29500267
PMCPMC5930380
OpenAlexW2789640865

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.