Evidence map›Paper›PMID 29500262›Full record

ArticleApplied and environmental microbiology2018

A Gene Homologous to rRNA Methylase Genes Confers Erythromycin and Clindamycin Resistance in Bifidobacterium breve.

Noelia Martínez, Roberto Luque, Christian Milani, Marco Ventura, Oscar Bañuelos, Abelardo Margolles

Open access · bronzeAbstract read
In one paragraph

Article in Applied and environmental microbiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.7field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 26 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Probiotic Properties ofFrontiers in microbiology · 2021
    Article
  6. Article
  7. Prevalence and Therapies of Antibiotic-Resistance inFrontiers in cellular and infection microbiology · 2020
    Review
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 2 countries.

Noelia MartínezDairy Research Institute of Asturias, Spanish National Research Council (IPLA-CSIC), Villaviciosa, Asturias, Spain.
Roberto LuqueBiosearch S.A., Granada, Spain.
Christian MilaniLaboratory of Probiogenomics, Department of Chemistry, Life Sciences and Environmental Sustainability, University of Parma, Parma, Italy.
Marco VenturaLaboratory of Probiogenomics, Department of Chemistry, Life Sciences and Environmental Sustainability, University of Parma, Parma, Italy.
Oscar BañuelosBiosearch S.A., Granada, Spain.
Abelardo MargollesDairy Research Institute of Asturias, Spanish National Research Council (IPLA-CSIC), Villaviciosa, Asturias, Spain amargolles@ipla.csic.es.
Biosearch Life (Spain) · ESUniversity of Parma · ITConsejo Superior de Investigaciones Científicas · ESInstituto de Productos Lácteos de Asturias · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bifidobacteria are mutualistic intestinal bacteria, and their presence in the human gut has been associated with health-promoting activities. The presence of antibiotic resistance genes in this genus is controversial, since, although bifidobacteria are nonpathogenic microorganisms, they could serve as reservoirs of resistance determinants for intestinal pathogens. However, until now, few antibiotic resistance determinants have been functionally characterized in this genus. In this work, we show that

Indexed as

Anti-Bacterial AgentsBacterial ProteinsBifidobacterium breveClindamycinDrug Resistance, BacterialErythromycinGastrointestinal MicrobiomeGene Transfer, HorizontalHumansIntestinesMethyltransferasesPhylogenyAnti-Bacterial AgentsBacterial ProteinsClindamycinErythromycinMethyltransferasesrRNA (adenosine-O-2'-)methyltransferaseBifidobacteriumBifidobacterium breveclindamycin resistanceerythromycin resistancemicrobiotaprobiotics

Identifiers

PMID29500262
PMCPMC5930361
OpenAlexW2792642479

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.