Evidence map›Paper›PMID 29500206›Full record

ArticleBMJ open2018

Developing a UK registry to investigate the role of cardiovascular magnetic resonance (CMR) in patients who activate the primary percutaneous coronary intervention (PPCI) pathway: a multicentre, feasibility study linking routinely collected electronic patient data.

Rachel C Brierley, Maria Pufulete, Jessica Harris, Chiara Bucciarelli-Ducci, John P Greenwood, Stephen Dorman, Richard Anderson, Chris A Rogers, Barnaby C Reeves

Abstract readMulticenter Study
PubMed Full text at PMC Publisher
In one paragraph

Article in BMJ open, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Rachel C BrierleyClinical Trials and Evaluation Unit, University of Bristol, Bristol, UK.
Maria PufuleteClinical Trials and Evaluation Unit, University of Bristol, Bristol, UK.ORCID 0000-0002-1775-1949
Jessica HarrisClinical Trials and Evaluation Unit, University of Bristol, Bristol, UK.
Chiara Bucciarelli-DucciNIHR Bristol Cardiovascular Research Unit, Bristol Heart Institute, University of Bristol, Bristol, UK.
John P GreenwoodMultidisciplinary Cardiovascular Research Centre and Leeds Institute of Cardiovascular and Metabolic Medicine, University of Leeds, Leeds, UK.
Stephen DormanNIHR Bristol Cardiovascular Research Unit, Bristol Heart Institute, University of Bristol, Bristol, UK.
Richard AndersonDepartment of Cardiology, University Hospital of Wales, Cardiff, UK.
Chris A RogersClinical Trials and Evaluation Unit, University of Bristol, Bristol, UK.
Barnaby C ReevesClinical Trials and Evaluation Unit, University of Bristol, Bristol, UK.

Funding

British Heart FoundationDepartment of Health 11/2003/58Medical Research Council MR/K025643/1
6 · The paper itself

Abstract

objectivesTo determine whether it is feasible to set up a national registry, linking routinely collected data from hospital information systems (HIS), to investigate the role of cardiovascular magnetic resonance (CMR) in patients who activate the primary percutaneous coronary intervention (PPCI) pathway.

designFeasibility prospective cohort study, to establish whether: (1) consent can be implemented; (2) data linkage and extraction from multiple HIS can be achieved for >90% of consented patients; (3) local data can be successfully linked with hospital episode data (Hospital Episode Statistics, HES; Patient Episode Database for Wales, PEDW) for >90% of consented patients and (4) the proportion of patients activating the PPCI pathway who get a CMR scan is ≥10% in hospitals with dedicated CMR facilities.

participantsPatients from four 24/7 PPCI hospitals in England and Wales (two with and two without a dedicated CMR facility) who activated the PPCI pathway and underwent an emergency coronary angiogram.

resultsConsent was successfully implemented at all hospitals (consent rates ranged from 59% to 74%) and 1670 participants were recruited. Data submission was variable: all hospitals submitted clinical data (for ≥82% of patients); only three hospitals submitted biochemistry data (for ≥98% of patients) and echocardiography data (for 34%-87% of patients); only one hospital submitted medications data (for 97% of patients). At the two CMR centres, 14% and 20% of patients received a CMR scan. Data submitted by hospitals were linked with HES and PEDW for 99% of all consented patients.

conclusionWe successfully consented patients but obtaining individual, opt-in consent would not be feasible for a national registry. Linkage of data from HIS with hospital episode data was feasible. However, data from HIS are not uniformly available/exportable and, in centres with a dedicated CMR facility, some referrals for CMR were for research rather than clinical purposes.

Indexed as

Magnetic Resonance ImagingPercutaneous Coronary InterventionAcute Coronary SyndromeAgedCoronary AngiographyEchocardiographyElectrocardiographyElectronic Health RecordsFeasibility StudiesFemaleHumansMaleMiddle AgedProspective StudiesRegistriesUnited Kingdomadult cardiologycardiovascular imaginginformation technology

Identifiers

PMID29500206
PMCPMC5855336

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.