Evidence map›Paper›PMID 29500190›Full record

ArticleThe Journal of cell biology2018

A homeostatic clock sets daughter centriole size in flies.

Mustafa G Aydogan, Alan Wainman, Saroj Saurya, Thomas L Steinacker, Anna Caballe, Zsofia A Novak, Janina Baumbach, Nadine Muschalik, Jordan W Raff

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In one paragraph

Article in The Journal of cell biology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 51 papers.

0numbers the graph read from it
0cells of the map it votes in
51citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

51 citing papers in PubMed.

  1. Article
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  4. Review
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  6. Review
  7. Repurposing Cell Cycle Oscillators for Multiciliated Cell Differentiation.Advances in experimental medicine and biology · 2026
    Review
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Regulation of organelle size and organization during development.Seminars in cell & developmental biology · 2023
    Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors.

Mustafa G AydoganSir William Dunn School of Pathology, University of Oxford, Oxford, England, UK.
Alan WainmanSir William Dunn School of Pathology, University of Oxford, Oxford, England, UK.ORCID 0000-0002-6292-4183
Saroj SauryaSir William Dunn School of Pathology, University of Oxford, Oxford, England, UK.ORCID 0000-0003-4057-0123
Thomas L SteinackerSir William Dunn School of Pathology, University of Oxford, Oxford, England, UK.
Anna CaballeSir William Dunn School of Pathology, University of Oxford, Oxford, England, UK.ORCID 0000-0002-3508-8474
Zsofia A NovakSir William Dunn School of Pathology, University of Oxford, Oxford, England, UK.
Janina BaumbachSir William Dunn School of Pathology, University of Oxford, Oxford, England, UK.
Nadine MuschalikSir William Dunn School of Pathology, University of Oxford, Oxford, England, UK.
Jordan W RaffSir William Dunn School of Pathology, University of Oxford, Oxford, England, UK jordan.raff@path.ox.ac.uk.ORCID 0000-0002-4689-1297

Funding

Wellcome Trust 104575Wellcome Trust 107457
6 · The paper itself

Abstract

Centrioles are highly structured organelles whose size is remarkably consistent within any given cell type. New centrioles are born when Polo-like kinase 4 (Plk4) recruits Ana2/STIL and Sas-6 to the side of an existing "mother" centriole. These two proteins then assemble into a cartwheel, which grows outwards to form the structural core of a new daughter. Here, we show that in early

Indexed as

S PhaseAnimalsBehavior, AnimalCell Cycle ProteinsCentriolesCircadian Rhythm Signaling Peptides and ProteinsDrosophila melanogasterDrosophila ProteinsEmbryo, NonmammalianHomeostasisLocomotionMicrotubule-Associated ProteinsMutationProtein BindingProtein Serine-Threonine KinasesProtein TransportAna2 protein, DrosophilaCell Cycle ProteinsCircadian Rhythm Signaling Peptides and ProteinsDrosophila ProteinsMicrotubule-Associated ProteinsProtein Serine-Threonine KinasesSak protein, DrosophilaSas-6 protein, Drosophila

Identifiers

PMID29500190
PMCPMC5881511

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.