Evidence map›Paper›PMID 29500114›Full record

ArticlePancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.]2018

Quality of life comparison between smokers and non-smokers with chronic pancreatitis.

Samuel Han, Boskey Patel, May Min, Lisa Bocelli, Joan Kheder, Amy Wachholtz, Wahid Wassef

Registry-linked trialAbstract readComparative Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.], 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04760847 (Intermittent Fasting as a Primary Means for Improving Quality of Life for Acute and Chronic Pancreatitis), which is not on this map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04760847 nanot yet recruitingnot on this mapstarted 2026, after this paper: background citation

Intermittent Fasting as a Primary Means for Improving Quality of Life for Acute and Chronic Pancreatitis

TypeinterventionalSponsorH. Lee Moffitt Cancer Center and Research InstituteRan2026 to 2026Enrolled64ConditionsPancreatitis, Pancreatitis, Acute, Pancreatitis, Chronic, Pancreas DiseaseArmsIntermittent Fasting, No intermittent fasting
3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Observational
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. The deleterious effects of smoking on the development and progression of chronic pancreatitis.Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] · 2022
    Review
  8. Clinical characteristics of smoking-related chronic pancreatitis.Frontiers in cellular and infection microbiology · 2022
    Article
  9. Article
  10. Observational
  11. Article
  12. Review
  13. Article
  14. Article
  15. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Samuel HanDivision of Gastroenterology and Hepatology, University of Colorado Anschutz Medical Center, Aurora, CO, USA. Electronic address: samuel.han@ucdenver.edu.
Boskey PatelDepartment of Internal Medicine, University of Massachusetts Medical Center, Worcester, MA, USA.
May MinDepartment of Internal Medicine, University of Massachusetts Medical Center, Worcester, MA, USA.
Lisa BocelliDivision of Gastroenterology, University of Massachusetts Medical Center, Worcester, MA, USA.
Joan KhederDivision of Gastroenterology, University of Massachusetts Medical Center, Worcester, MA, USA.
Amy WachholtzDepartment of Psychology, University of Colorado, Denver, CO, USA.
Wahid WassefDivision of Gastroenterology, University of Massachusetts Medical Center, Worcester, MA, USA.

Funding

GASTROINTESTINAL DISEASE TRAINING GRANTT32DK007038 · NIDDK · UNIVERSITY OF COLORADO DENVER · PI COLGAN, SEAN P · 1986 to 2020
$3.5M
Co-Morbid Opioid Addiction and Chronic PainK23DA030397 · NIDA · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI WACHHOLTZ, AMY B · 2011 to 2015
$685k
NIDA NIH HHS K23 DA030397NIDDK NIH HHS T32 DK007038
6 · The paper itself

Abstract

objectivesThe aim of this study was to evaluate the impact of smoking on quality of life in patients with chronic pancreatitis.

methodsThis is a cross-sectional study of chronic pancreatitis patients followed at a single institution comparing smokers with non-smokers. The primary outcome was quality of life and secondary outcomes included demographics, drug and alcohol use, anxiety and depression, pain level, nutritional status, and metabolic factors.

results48 smokers and 45 non-smokers participated in this study. Smokers had a worse overall quality of life and higher rates of opioid addiction and depression than non-smokers. Smokers also had less racial diversity, lower education levels, and higher amounts of narcotic use than non-smokers. Furthermore, smokers had a lower BMI and a higher proportional use of pancreatic enzyme replacement therapy. Smoking was found to be independently associated with worse quality of life on multivariable regression.

conclusionsThe worse overall quality of life and higher rates of depression and anxiety create cause for concern in chronic pancreatitis patients who smoke. Smoking cessation should be an important target in chronic pancreatitis patients. Multicenter, multiethnic studies are needed to further elucidate this relationship.

Indexed as

Quality of LifeAdultAgedAnxietyCohort StudiesCross-Sectional StudiesDepressionEducational StatusEnzyme Replacement TherapyFemaleHumansMaleMiddle AgedNarcoticsNutritional StatusPancreatitis, ChronicNarcoticsChronic pancreatitisOpioid addictionQuality of lifeSmoking

Identifiers

PMID29500114
PMCPMC5879011

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.