ReviewAdvances in chronic kidney disease2018
Kidney Function in Obesity-Challenges in Indexing and Estimation.
Review in Advances in chronic kidney disease, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 50 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
50 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Prenatal metal(loid) exposure and preterm birth: a systematic review of the epidemiologic evidence.Journal of exposure science & environmental epidemiology · 2025Pooled it
- Long-term kidney outcomes of semaglutide in obesity and cardiovascular disease in the SELECT trial.Nature medicine · 2024Trial
- Severe obesity and the impact of medical weight loss on estimated glomerular filtration rate.PloS one · 2020Trial
- Medications Influencing Serum Cystatin C Independent of Measured GFR.Journal of the American Society of Nephrology : JASN · 2026Article
- Impact of creatine supplementation on kidney health: a systematic review and meta-analysis.International urology and nephrology · 2026Review
- Body Surface Area Indexing Attenuates Apparent Early eGFR Decline After Sleeve Gastrectomy: A Retrospective Cohort Study.Journal of clinical medicine · 2026Article
- Obesity-related glomerulopathy, A growing kidney burden in the obesity pandemic.Clinical and experimental nephrology · 2026Review
- Impact of residual kidney function on hemodynamic changes during induction of general anesthesia in hemodialysis patients: a retrospective observational study.Journal of anesthesia · 2026Article
- A Novel Murine Model Integrating Peripheral Arterial Disease and Multiorgan Dysfunction: Unraveling Cardiovascular-Kidney-Metabolic Complexity.Kidney360 · 2026Article
- Associations of metabolic dysfunction-associated steatotic liver disease and significant fibrosis phenotypes with glomerular hyperfiltration defined by indexed eGFR.Frontiers in nutrition · 2026Article
- Article
- Obesity, Underweight, and Accuracy of eGFR Using Cystatin C and Creatinine in a Northern European Population.Journal of the American Society of Nephrology : JASN · 2025Article
- Impact of GFR on Mortality Risk After Biliopancreatic Diversion: Challenges and Pitfalls for the Clinician.Obesity surgery · 2025Article
- Size-selective glomerular filtration as a hallmark of premature kidney ageing in nondiabetic individuals.Clinical kidney journal · 2025Article
- Article
- Effect of Glomerular Hyperfiltration on Incident Cardiovascular Disease in Patients with Type 2 Diabetes Mellitus.Clinical journal of the American Society of Nephrology : CJASN · 2025Article
- Serum Creatinine Level in Relation to Intraluminal Thrombus and Abdominal Aortic Aneurysm Size.Journal of clinical medicine · 2025Article
- Obesity-Related Chronic Kidney Disease: From Diagnosis to Treatment.Diagnostics (Basel, Switzerland) · 2025Review
- The relationship between low levels of albuminuria and mortality among adults without major cardiovascular risk factors.European journal of preventive cardiology · 2024Article
- Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
As the prevalence of obesity continues to increase worldwide, an increasing number of people are at risk for kidney disease. Thus, there is a critical need to understand how best to assess kidney function in this population, and several challenges exist. The convention of indexing glomerular filtration rate (GFR) to body surface area (BSA) attempts to normalize exposure to metabolic wastes across populations of differing body size. In obese individuals, this convention results in a significantly lower indexed GFR than unindexed GFR, which has practical implications for drug dosing. Recent data suggest that "unindexing" estimated GFR (multiplying by BSA/1.73 m
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.