Evidence map›Paper›PMID 29499692›Full record

ArticleBMC musculoskeletal disorders2018

The influence of preoperative determinants on quality of life, functioning and pain after total knee and hip replacement: a pooled analysis of Dutch cohorts.

Stefanie N Hofstede, Maaike G J Gademan, Theo Stijnen, Rob G H H Nelissen, Perla J Marang-van de Mheen, ARGON-OPTIMA study group

Abstract readMulticenter Study
In one paragraph

Article in BMC musculoskeletal disorders, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Stefanie N HofstedeDepartment of Orthopaedics, Leiden University Medical Center, Leiden, The Netherlands.
Maaike G J GademanDepartment of Orthopaedics, Leiden University Medical Center, Leiden, The Netherlands.
Theo StijnenDepartment of Medical Statistics, Leiden University Medical Center, Leiden, The Netherlands.
Rob G H H NelissenDepartment of Orthopaedics, Leiden University Medical Center, Leiden, The Netherlands.
Perla J Marang-van de MheenMedical Decision Making, Department of Biomedical Data Sciences, Leiden University Medical Center, J10-S, PO Box 9600, 2300 RC, Leiden, The Netherlands. p.j.marang@lumc.nl.
ARGON-OPTIMA study group

Funding

Reumafonds BP 12-3-401
6 · The paper itself

Abstract

backgroundPrevious research has identified preoperative determinants that predict health related quality of life (HRQoL), functioning and pain after total knee or hip arthroplasty (TKA/THA), but these differed between studies and had opposite directions. This may be due to lack of power and not adjusting for confounders. The present study aims to identify the preoperative determinants that influence health related quality of life (HRQoL), functioning and pain after total knee or hip arthroplasty (TKA/THA).

methodsWe pooled individual patient from 20 cohorts with OA patients data (n = 1783 TKA and n = 2400 THA) in the Netherlands. We examined the influence of age, gender, BMI and preoperative values of HRQoL, functioning and pain on postoperative status and total improvement. Linear mixed models were used to estimate the effect of each preoperative variable on a particular outcome for each cohort separately. These effects were pooled across cohorts using a random effects model.

resultsFor each increase in preoperative point in HRQoL, the postoperative HRQoL increased by 0.51 points in TKA and 0.37 points in THA (SF-36 scale). Similarly, each point increase in preoperative functioning, resulted in a higher postoperative functioning of 0.31 (TKA) and 0.21 (THA) points (KOOS/HOOS-ADL scale). For pain this was 0.18 (TKA) and 0.15 (THA) points higher (KOOS/HOOS-pain scale) (higher means less pain). Even though patients with better preoperative values achieved better postoperative outcomes, their improvement was smaller. Women and patients with a higher BMI had more pain after a TKA and THA. Higher age and higher BMI was associated with lower postoperative HRQoL and functioning and more pain after a THA.

conclusionsPatients with a better preoperative health status have better outcomes, but less improvement. Even though the independent effects may seem small, combined results of preoperative variables may result in larger effects on postoperative outcomes.

Indexed as

Quality of LifeRecovery of FunctionAgedArthroplasty, Replacement, HipArthroplasty, Replacement, KneeCohort StudiesFemaleHumansMaleMiddle AgedNetherlandsPain MeasurementPostoperative PainPreoperative CareProspective StudiesFunctioningPainPostoperativePreoperativeQuality of lifeTotal hip replacementTotal knee replacement

Identifiers

PMID29499692
PMCPMC5833034

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.