SynthesisPloS one2018
Short- and long-term prognostic value of hyponatremia in patients with acute coronary syndrome: A systematic review and meta-analysis.
Synthesis in PloS one, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed.
- Article
- Construction of risk predictive models for postoperative hyponatremia in colorectal cancer patients.American journal of cancer research · 2026Article
- Association between serum sodium and the risk of sepsis-related liver injury: a cross-sectional study based on the MIMIC-IV database.BMC infectious diseases · 2025Article
- Hyponatraemia in ageing.Nature reviews. Endocrinology · 2025Review
- Long-Term Clinical Relevance of Hyponatremia Identified During Acute Phase of Myocardial Infarction.Journal of clinical medicine · 2025Article
- Hyponatremia after COVID-19 is frequent in the first year and increases re-admissions.Scientific reports · 2024Observational
- Hyponatremia and Cancer: From Bedside to Benchside.Cancers · 2023Review
- Hyponatremia in patients with arterial hypertension: pathophysiology and management.Archives of medical science : AMS · 2023Article
- Impact of cardiac and noncardiac cirrhosis on coronary revascularization outcomes from the National Inpatient Sample, 2016 to 2018.Proceedings (Baylor University. Medical Center) · 2023Article
- A step-by-step guide for the diagnosis and management of hyponatraemia in patients with stroke.Therapeutic advances in endocrinology and metabolism · 2023Review
- Integrated bioinformatics and machine learning algorithms reveal the critical cellular senescence-associated genes and immune infiltration in heart failure due to ischemic cardiomyopathy.Frontiers in immunology · 2023Article
- Early prognostic impact of serum sodium level among out-of-hospital cardiac arrest patients: a nationwide multicentre observational study in Japan (the JAAM-OHCA registry).Heart and vessels · 2022Observational
- Management of Acute Coronary Syndrome in Patients with Liver Cirrhosis.American journal of cardiovascular drugs : drugs, devices, and other interventions · 2022Review
- Hyponatremia and Oxidative Stress.Antioxidants (Basel, Switzerland) · 2021Review
- Electrolytes and clinical outcomes in patients with acute ischemic stroke or transient ischemic attack.Annals of translational medicine · 2021Article
- Hyponatremia as a prognostic factor in non-small cell lung cancer: a systematic review and meta-analysis.Translational lung cancer research · 2021Article
- Abnormal serum chloride is associated with increased mortality among unselected cardiac intensive care unit patients.PloS one · 2021Article
- Abnormal Serum Sodium is Associated With Increased Mortality Among Unselected Cardiac Intensive Care Unit Patients.Journal of the American Heart Association · 2020Article
- Prognostic Significance of Hyponatremia in ST-elevation Myocardial Infarction/Heart Failure Patients.Cureus · 2019Review
- Shape of the association between preoperative hemoglobin level and postoperative outcomes in patients undergoing primary arthroplasty.Canadian journal of surgery. Journal canadien de chirurgieArticle
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Hyponatremia is relevant to heart failure, liver cirrhosis and stroke, but the prognostic value of serum sodium levels in patients with acute coronary syndrome are still unclear. So we did a systematic review and meta-analysis to assess the prognostic value of hyponatremia on adverse events in patients after ACS. We systematically searched PubMed, Embase and Cochrane Library to find literatures which studied the prognostic value of hyponatremia in patients with ACS. Our main endpoints were the all-cause mortality and heart failure in the short- and long-term. Of 369 identified studies, 20 studies were included in our analysis. Compared with the normal natrium, hyponatremia was significantly associated with the increased risks of all-cause mortality within 30 days (RR: 2.18; 95%CI: 1.96-2.42) and during the follow-ups (HR: 1.74; 95%CI: 1.56-1.942). For the second endpoint of short- and long-term heart failure, the pooled effect sizes in hyponatremia patients were 1.72(95%CI: 1.38-2.14) and 1.69(95%CI: 1.12-2.55) respectively. In conclusion, hyponatremia has a significant prognostic value for short- and long-term adverse event in patients after ACS, the dynamic monitoring of serum sodium levels may could help physicians to identify high risk ACS patients and to stratify risk for optimal management.
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