ArticlePloS one2018
Resting heart rate is an independent predictor of advanced colorectal adenoma recurrence.
Article in PloS one, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it, 25 citations in OpenAlex.
- Resting heart rate and risk of type 2 diabetes: A prospective cohort study and meta-analysis.Diabetes/metabolism research and reviews · 2019Pooled it
- Recurrent unexplained resting sinus tachycardia as a marker of adverse cardiovascular outcomes in cancer patients.American heart journal plus : cardiology research and practice · 2026Article
- Prognostic role of resting heart rate in patients with colorectal cancer.Journal of gastrointestinal oncology · 2026Article
- Navigating the Terrain of Post-Polypectomy Surveillance: Charting the Complex Landscape of Guidelines and Recurrence Risks.Canadian journal of gastroenterology & hepatology · 2026Review
- Association between resting heart rate and prognosis in patients with gastric cancer.Scientific reports · 2025Article
- Cancer-Induced Resting Sinus Tachycardia: An Overlooked Clinical Diagnosis.Oncology reviews · 2024Review
- Evidence of sex differences in cancer-related cardiac complications in mouse models of pancreatic and liver cancer.Physiological reports · 2023Article
- Initial in-hospital heart rate is associated with long-term survival in patients with acute ischemic stroke.Clinical research in cardiology : official journal of the German Cardiac Society · 2022Article
- The utility of resting pulse rate in defining high blood pressure among adolescents in Mbarara municipality, Uganda.Journal of human hypertension · 2021Article
- Pericardial Effusions in Patients With Cancer: Anesthetic Management and Survival Outcomes.Journal of cardiothoracic and vascular anesthesia · 2021Observational
- Article
- [Tumor effects on the heart and circulation].Der Internist · 2020Review
- Risk Factors for Recurrent Colorectal Polyps.Gut and liver · 2020Review
- Increased resting heart rate and prognosis in treatment-naïve unselected cancer patients: results from a prospective observational study.European journal of heart failure · 2020Observational
- Oncology and Cardiac Rehabilitation: An Underrated Relationship.Journal of clinical medicine · 2020Review
- Recent advances in cardio-oncology: a report from the 'Heart Failure Association 2019 and World Congress on Acute Heart Failure 2019'.ESC heart failure · 2019Article
- Association between Resting Heart Rate and Colorectal Cancer: Results from a Case-Controlled Study.International journal of environmental research and public health · 2019Article
- Greater Well-Being in More Physically Active Cancer Patients Who Are Enrolled in Supportive Care Services.Integrative cancer therapiesArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND AND
aimHigh heart rate is an independent predictor of total cancer incidence and all-cause mortality in patients with cancer. We aimed to evaluate the impact of resting heart rate on the recurrence of colorectal polyp, using long-term surveillance follow-up data of colorectal cancer survivors.
methodsThree hundred patients were selected from the colorectal cancer survivor cohort of Severance Hospital, Seoul, Korea. Resting heart rate, physical activity, and body composition analysis at the time of 5-year survival, and clinical data including colonoscopy surveillance results were collected for mean follow-up duration of 8 years.
resultsPatients with a high resting heart rate showed a significantly higher recurrence rate of advanced adenoma than those with a low resting heart rate (quartile 1, 45-66 beats per minute (b.p.m.); quartile 2, 67-73 b.p.m.; quartile 3, 74-80 b.p.m.; quartile 4, 81-120 b.p.m.; 3.8% vs. 7.9% vs. 10.0% vs. 14.7%, p for trend = 0.018). After adjustment for various risk factors, patients in the highest quartile of resting heart rate (≥ 81 b.p.m.) had a significantly higher risk of advanced adenoma recurrence (hazard ratio [HR]: 6.183, 95% confidence interval [CI]: 1.181-32.373, p = 0.031), compared to those in the lowest quartile (≤ 66 b.p.m.). In subgroup analysis, the association of resting heart rate with advanced adenoma recurrence appeared to be stronger among patients who had more than normal body fat mass or sedentary life style.
conclusionsElevated resting heart rate was independently associated with a higher rate of advanced adenoma recurrence in colorectal cancer survivors.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.