ArticleHuman brain mapping2018
Aberrant functional network connectivity in psychopathy from a large (N = 985) forensic sample.
Article in Human brain mapping, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 3 of them syntheses that pooled it.
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Who cites it
29 citing papers in PubMed, 3 syntheses or guidelines pooled it, 69 citations in OpenAlex.
- Using physiological biomarkers in forensic psychiatry: a scoping review.Frontiers in psychiatry · 2025Pooled it
- Psychopathy and medial frontal cortex: A systematic review reveals predominantly null relationships.Neuroscience and biobehavioral reviews · 2024Pooled it
- Functional neural correlates of psychopathy: a meta-analysis of MRI data.Translational psychiatry · 2020Pooled it
- Resting-state brain function and its modulation by intranasal oxytocin in antisocial personality disorder with and without psychopathy.Scientific reports · 2026Article
- Narcissistic and Antisocial Personality Traits Are Both Encoded in the Triple Network: Connectomics Evidence.Psychophysiology · 2025Article
- Cortical structure in relation to empathy and psychopathy in 800 incarcerated men.bioRxiv : the preprint server for biology · 2025Article
- White Matter Correlates of Psychopathic Traits in a Japanese Community Sample: Sex Matters!The European journal of neuroscience · 2025Article
- Alcohol attention bias modulates neural engagement during moral processing.Social neuroscience · 2024Article
- Impaired salience network switching in psychopathy.Behavioural brain research · 2023Article
- Neural Correlates of Psychopathic Traits in Schizophrenia: fMRI Study of Response Inhibition in Persistently Violent Patients.Schizophrenia bulletin open · 2023Article
- Different whole-brain functional connectivity correlates of reactive-proactive aggression and callous-unemotional traits in children and adolescents with disruptive behaviors.NeuroImage. Clinical · 2023Article
- Aberrant resting-state functional connectivity associated with childhood trauma among juvenile offenders.NeuroImage. Clinical · 2023Article
- Psychopathic traits and altered resting-state functional connectivity in incarcerated adolescent girls.Frontiers in neuroimaging · 2023Article
- A multidimensional examination of psychopathy traits and gray matter volume in adults.Social cognitive and affective neuroscience · 2022Article
- Aberrant resting-state functional connectivity in incarcerated women with elevated psychopathic traits.Frontiers in neuroimaging · 2022Article
- Callous-unemotional traits and reduced default mode network connectivity within a community sample of children.Development and psychopathology · 2021Article
- Reduced neural responsiveness to looming stimuli is associated with increased aggression.Social cognitive and affective neuroscience · 2021Article
- Aggression subtypes relate to distinct resting state functional connectivity in children and adolescents with disruptive behavior.European child & adolescent psychiatry · 2021Article
- Gray matter asymmetry in the orbitofrontal cortex in relation to psychopathic traits in adolescents.Journal of psychiatric research · 2021Article
- Neural responses to morally laden interactions in female inmates with psychopathy.NeuroImage. Clinical · 2021Article
Corrections and comments
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Authors and funding
15 authors at 4 institutions in 1 country.
Funding
Abstract
Psychopathy is a personality disorder characterized by antisocial behavior, lack of remorse and empathy, and impaired decision making. The disproportionate amount of crime committed by psychopaths has severe emotional and economic impacts on society. Here we examine the neural correlates associated with psychopathy to improve early assessment and perhaps inform treatments for this condition. Previous resting-state functional magnetic resonance imaging (fMRI) studies in psychopathy have primarily focused on regions of interest. This study examines whole-brain functional connectivity and its association to psychopathic traits. Psychopathy was hypothesized to be characterized by aberrant functional network connectivity (FNC) in several limbic/paralimbic networks. Group-independent component and regression analyses were applied to a data set of resting-state fMRI from 985 incarcerated adult males. We identified resting-state networks (RSNs), estimated FNC between RSNs, and tested their association to psychopathy factors and total summary scores (Factor 1, interpersonal/affective; Factor 2, lifestyle/antisocial). Factor 1 scores showed both increased and reduced functional connectivity between RSNs from seven brain domains (sensorimotor, cerebellar, visual, salience, default mode, executive control, and attentional). Consistent with hypotheses, RSNs from the paralimbic system-insula, anterior and posterior cingulate cortex, amygdala, orbital frontal cortex, and superior temporal gyrus-were related to Factor 1 scores. No significant FNC associations were found with Factor 2 and total PCL-R scores. In summary, results suggest that the affective and interpersonal symptoms of psychopathy (Factor 1) are associated with aberrant connectivity in multiple brain networks, including paralimbic regions.
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Registered trials
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