Evidence map›Paper›PMID 29498658›Full record

ArticleMolecules (Basel, Switzerland)2018

Enzyme Kinetics and Molecular Docking Studies on Cytochrome 2B6, 2C19, 2E1, and 3A4 Activities by Sauchinone.

Eun Chae Gong, Satya Chea, Anand Balupuri, Nam Sook Kang, Young-Won Chin, Young Hee Choi

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.9field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 21 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Review
  5. Drug-herb Synergistic Interactions between Clopidogrel and Natural Medicine.Cardiovascular & hematological agents in medicinal chemistry · 2024
    Review
  6. Article
  7. Review
  8. Interactions between clopidogrel and traditional Chinese medicine.Journal of thrombosis and thrombolysis · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Eun Chae GongCollege of Pharmacy and Intergrated Research Institute for Drug Development, Dongguk University-Seoul, 32 Dongguk-lo, Ilsandong-gu, Goyang, Gyeonggi-do 10326, Korea. dmsco3901@hanmail.net.
Satya CheaCollege of Pharmacy and Intergrated Research Institute for Drug Development, Dongguk University-Seoul, 32 Dongguk-lo, Ilsandong-gu, Goyang, Gyeonggi-do 10326, Korea. satyachea168@gmail.com.
Anand BalupuriGraduate School of New Drug Discovery and Development, Chungnam National University, Daejeon 305-764, Korea. balupuri@cnu.ac.kr.
Nam Sook KangGraduate School of New Drug Discovery and Development, Chungnam National University, Daejeon 305-764, Korea.
Young-Won ChinCollege of Pharmacy and Intergrated Research Institute for Drug Development, Dongguk University-Seoul, 32 Dongguk-lo, Ilsandong-gu, Goyang, Gyeonggi-do 10326, Korea.
Young Hee ChoiCollege of Pharmacy and Intergrated Research Institute for Drug Development, Dongguk University-Seoul, 32 Dongguk-lo, Ilsandong-gu, Goyang, Gyeonggi-do 10326, Korea. choiyh@dongguk.edu.
Dongguk University · KRChungnam National University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Sauchinone, an active lignan isolated from the aerial parts of

Indexed as

Herb-Drug InteractionsAnimalsAnti-Inflammatory AgentsAnti-Obesity AgentsBenzopyransBinding SitesCatalytic DomainChlorzoxazoneClopidogrelCyclobutanesCytochrome P-450 CYP2B6Cytochrome P-450 CYP2C19Cytochrome P-450 CYP2E1Cytochrome P-450 CYP3ACytochrome P-450 Enzyme InhibitorsDioxolesAnti-Inflammatory AgentsAnti-Obesity AgentsBenzopyransChlorzoxazoneClopidogrelCyclobutanesCYP2B6 protein, humanCYP2C19 protein, humanCYP3A4 protein, humancytochrome P-450 2E1, mouseCytochrome P-450 CYP2B6Cytochrome P-450 CYP2C19Cytochrome P-450 CYP2E1Cytochrome P-450 CYP3ACytochrome P-450 Enzyme InhibitorsDioxolesHypoglycemic AgentsPlant ExtractssauchinonesibutramineTiclopidineCYP450dockingherb-drug interactionhuman liver microsomemetabolic inhibitionsauchinoneSaururus chinensis

Identifiers

PMID29498658
PMCPMC6017976
OpenAlexW2793636761

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.