Evidence map›Paper›PMID 29498645›Full record

ReviewAntioxidants (Basel, Switzerland)2018

The Energy Costs of Prematurity and the Neonatal Intensive Care Unit (NICU) Experience.

John B C Tan, Danilo S Boskovic, Danilyn M Angeles

Registry-linked trialOpen access · goldAbstract readReview
In one paragraph

Review in Antioxidants (Basel, Switzerland), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04368767 (A Pilot Randomized Controlled Trial of the Effects of Daily Skin-to-skin Contact Compared to Standard Care on the Stress Responses of Late Preterm Infants in the First Week of Life), which is not on this map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04368767 nacompletednot on this mapstarted 2020, after this paper: background citation

A Pilot Randomized Controlled Trial of the Effects of Daily Skin-to-skin Contact Compared to Standard Care on the Stress Responses of Late Preterm Infants in the First Week of Life

TypeinterventionalSponsorUniversity of California, San FranciscoRan2020 to 2020Enrolled8ConditionsPremature Baby 33 to 36 Weeks, Mother-Infant Interaction, Oxidative StressArmsSkin-to-skin
3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 33 citations in OpenAlex.

  1. Cerebral fuels within the first week of life in very preterm infants: a cohort study.Archives of disease in childhood. Fetal and neonatal edition · 2026
    Trial
  2. Trial
  3. Review
  4. Article
  5. Article
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  8. Human milk fortification and use of infant formulas to support growth in the neonatal intensive care unit.Nutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition · 2023
    Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
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  16. Differential effects of the retinopathy of prematurity exam on the physiology of premature infants.Journal of perinatology : official journal of the California Perinatal Association · 2019
    Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

John B C TanDivision of Biochemistry, Department of Basic Sciences, Loma Linda University, Loma Linda, CA 92350, USA. jctan@llu.edu.
Danilo S BoskovicDivision of Biochemistry, Department of Basic Sciences, Loma Linda University, Loma Linda, CA 92350, USA. dboskovic@llu.edu.
Danilyn M AngelesDivision of Physiology, Department of Basic Sciences, Loma Linda University, Loma Linda, CA 92350, USA. dangeles@llu.edu.ORCID 0000-0002-0997-0295
Loma Linda University · US

Funding

Pain and Hypoxia in Premature NeonatesR01NR011209 · NINR · LOMA LINDA UNIVERSITY · PI ANGELES, DANILYN MAG-AKAT · 2009 to 2017
$2.9M
NINR NIH HHS R01 NR011209
6 · The paper itself

Abstract

Premature neonates are in an energy deficient state due to (1) oxygen desaturation and hypoxia events, (2) painful and stressful stimuli, (3) illness, and (4) neurodevelopmental energy requirements. Failure to correct energy deficiency in premature infants may lead to adverse effects such as neurodevelopmental delay and negative long-term metabolic and cardiovascular outcomes. The effects of energy dysregulation and the challenges that clinicians in the Neonatal Intensive Care Unit (NICU) face in meeting the premature infant's metabolic demands are discussed. Specifically, the focus is on the effects of pain and stress on energy homeostasis. Energy deficiency is a complex problem and requires a multi-faceted solution to promote optimum development of premature infants.

Indexed as

energynutritionpainpremature neonatesucrose

Identifiers

PMID29498645
PMCPMC5874523
OpenAlexW2793318666

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.