Evidence map›Paper›PMID 29498537›Full record

ArticleJournal of alternative and complementary medicine (New York, N.Y.)2018

Complementary and Alternative Medicine Usage by Multiple Sclerosis Patients: Results from a Prospective Clinical Study.

Soohyun Kim, Lawrence Chang, Bianca Weinstock-Guttman, Sirin Gandhi, Dejan Jakimovski, Ellen Carl, Robert Zivadinov, Murali Ramanathan

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of alternative and complementary medicine (New York, N.Y.), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
4.8field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 44 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. Article
  16. Review
  17. Article
  18. Article
  19. A Review of Herbal Therapy in Multiple Sclerosis.Advanced pharmaceutical bulletin · 2018
    Review
  20. The preventive effect ofAvicenna journal of phytomedicine
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Soohyun Kim1 Department of Pharmaceutical Sciences, State University of New York , Buffalo, Buffalo, New York.
Lawrence Chang1 Department of Pharmaceutical Sciences, State University of New York , Buffalo, Buffalo, New York.
Bianca Weinstock-Guttman2 Department of Neurology, State University of New York , Buffalo, Buffalo, New York.
Sirin Gandhi2 Department of Neurology, State University of New York , Buffalo, Buffalo, New York.
Dejan Jakimovski2 Department of Neurology, State University of New York , Buffalo, Buffalo, New York.
Ellen Carl2 Department of Neurology, State University of New York , Buffalo, Buffalo, New York.
Robert Zivadinov2 Department of Neurology, State University of New York , Buffalo, Buffalo, New York.
Murali Ramanathan1 Department of Pharmaceutical Sciences, State University of New York , Buffalo, Buffalo, New York.
University at Buffalo, State University of New York · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo investigate the factors associated with complementary and alternative medicine (CAM) usage by multiple sclerosis (MS) patients. Design, Setting/Location: Single-center, prospective clinical study at an academic MS center in the northeastern United States.

methodsThis study included CAM data from 524 MS patients and 304 healthy controls (HC) enrolled in a prospective study of clinical, neuroimaging, and environmental risk factors in MS at an academic MS Center. Clinical, neuroimaging, and disease-modifying treatment data were obtained. In addition, data on usage of CAM modalities, including acupuncture, aromatherapy, Ayurveda, Chinese herbal medicine, chiropractor, electromagnetic therapy, homeopathy, hypnosis, massage, naturopathy, Qi gong, Reiki, therapeutic touch, and bee stings were collected in an in-person interview.

resultsThe percentages of HC reporting usage of any CAM (32%) was similar to that in MS patients after diagnosis (30.5%). The usage of any CAM was higher in MS patients after MS diagnosis compared to before MS diagnosis (p < 0.001). The three most frequently used CAM for MS patients after MS diagnosis and HC were chiropractor, massage, and acupuncture. The most frequent reasons for CAM use were MS symptom relief, back problems, and pain. In multivariate analysis, female gender, higher education level, MS disease course, and not currently on disease-modifying therapies (DMT) treatment status were associated with CAM usage.

conclusionsGender, education level, DMT treatment status, and MS disease course are associated with CAM usage in MS patients. Ever-CAM usage patterns in MS patients are similar to those in HC.

Indexed as

Complementary TherapiesAdultFemaleHumansMaleMiddle AgedMultiple SclerosisNew YorkProspective Studiesalternative medicinecomplementary medicinedisease-modifying therapymultiple sclerosis

Identifiers

PMID29498537
PMCPMC6006417
OpenAlexW2792622939

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.