ArticleDiabetes, obesity & metabolism2018
Role of bicarbonate supplementation on urine uric acid crystals and diabetic tubulopathy in adults with type 1 diabetes.
Article in Diabetes, obesity & metabolism, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed, 17 citations in OpenAlex.
- MSU crystallization promotes fibroblast proliferation and renal fibrosis in diabetic nephropathy via the ROS/SHP2/TGFβ pathway.Scientific reports · 2024Article
- Asymptomatic hyperuricaemia in chronic kidney disease: mechanisms and clinical implications.Clinical kidney journal · 2023Review
- Longitudinal uric acid has nonlinear association with kidney failure and mortality in chronic kidney disease.Scientific reports · 2023Article
- Uric Acid and Chronic Kidney Disease: Still More to Do.Kidney international reports · 2023Review
- Inhaled silica nanoparticles cause chronic kidney disease in rats.American journal of physiology. Renal physiology · 2022Article
- Hyperuricemia and Progression of Chronic Kidney Disease: A Review from Physiology and Pathogenesis to the Role of Urate-Lowering Therapy.Diagnostics (Basel, Switzerland) · 2021Review
- Mini Review: Reappraisal of Uric Acid in Chronic Kidney Disease.American journal of nephrology · 2021Review
- New-Onset Gout as an Independent Risk Factor for Returning to Dialysis After Kidney Transplantation.Transplantation direct · 2020Article
- Uric Acid and Hypertension: An Update With Recommendations.American journal of hypertension · 2020Review
- The association of renal tubular inflammatory and injury markers with uric acid excretion in chronic kidney disease patients.International urology and nephrology · 2020Article
- The case for uric acid-lowering treatment in patients with hyperuricaemia and CKD.Nature reviews. Nephrology · 2019Review
- The perils of rehydrating with soft drinks following heat and exercise.American journal of physiology. Regulatory, integrative and comparative physiology · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
15 authors at 7 institutions in 2 countries.
Funding
Abstract
Uricosuria and crystallization are increasingly recognized risk factors for diabetic tubulopathy. This pilot clinical trial aimed to determine the acute effect of urinary alkalinization using oral sodium bicarbonate (NaHCO
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.