Evidence map›Paper›PMID 29498196›Full record

ArticleAmerican journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons2018

Prescription opioid use before and after kidney transplant: Implications for posttransplant outcomes.

K L Lentine, N N Lam, A S Naik, D A Axelrod, Z Zhang, V R Dharnidharka, G P Hess, D L Segev, R Ouseph, H Randall and 6 more

Abstract read
In one paragraph

Article in American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Review
  6. Sleep disorders and sleep medications as risk factors for dementia in kidney transplant recipients: A retrospective cohort study.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2025
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Balancing Risk and Uncertain Benefit in Pharmacotherapy for Pain in Kidney Transplant Recipients.Clinical journal of the American Society of Nephrology : CJASN · 2023
    Article
  12. Gabapentin, Concomitant Prescription of Opioids, and Benzodiazepines among Kidney Transplant Recipients.Clinical journal of the American Society of Nephrology : CJASN · 2023
    Article
  13. Review
  14. Article
  15. Survival implications of prescription opioid and benzodiazepine use in lung transplant recipients: Analysis of linked transplant registry and pharmacy fill records.The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation · 2021
    Article
  16. Opioids and Kidney Transplantation.Seminars in nephrology · 2021
    Review
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

K L LentineCenter for Abdominal Transplantation, Saint Louis University School of Medicine, St. Louis, MO, USA.
N N LamDivision of Nephrology, University of Alberta, Edmonton, AB, Canada.
A S NaikDivision of Nephrology, Department of Medicine, University of Michigan, Ann Arbor, MI, USA.
D A AxelrodDivision of Transplantation, Department of Surgery, Lahey Clinic, Burlington, MA, USA.
Z ZhangCenter for Abdominal Transplantation, Saint Louis University School of Medicine, St. Louis, MO, USA.
V R DharnidharkaTransplant Nephrology, Washington University School of Medicine, St. Louis, MO, USA.
G P HessSymphony Health, Conshohocken, PA, USA.
D L SegevCenter for Transplantation, Johns Hopkins School of Medicine, Baltimore, MD, USA.
R OusephCenter for Abdominal Transplantation, Saint Louis University School of Medicine, St. Louis, MO, USA.
H RandallCenter for Abdominal Transplantation, Saint Louis University School of Medicine, St. Louis, MO, USA.
T AlhamadTransplant Nephrology, Washington University School of Medicine, St. Louis, MO, USA.
R DevrajSchool of Pharmacy, Southern Illinois University, Edwardsville, IL, USA.
R GadiCenter for Abdominal Transplantation, Saint Louis University School of Medicine, St. Louis, MO, USA.
B L KasiskeDepartment of Medicine, Hennepin County Medical Center, Minneapolis, MN, USA.
D C BrennanCenter for Transplantation, Johns Hopkins School of Medicine, Baltimore, MD, USA.
M A SchnitzlerCenter for Abdominal Transplantation, Saint Louis University School of Medicine, St. Louis, MO, USA.

Funding

Long-Term Health Outcomes After Live Kidney Donation in African AmericansR01DK096008 · NIDDK · JOHNS HOPKINS UNIVERSITY · PI SEGEV, DORRY L. · 2013 to 2017
$3.8M
Choosing Immune Suppression in Renal Transplantation by Efficacy and MorbidityR01DK102981 · NIDDK · WASHINGTON UNIVERSITY · PI DHARNIDHARKA, VIKAS R. · 2014 to 2018
$1.9M
HRSA HHS HHSH250201000018CNIDDK NIH HHS R01 DK096008NIDDK NIH HHS R01-DK096008NIDDK NIH HHS R01 DK102981
6 · The paper itself

Abstract

Evolving literature suggests that the epidemic of prescription opioid use affects the transplant population. We examined a novel database wherein national U.S. transplant registry records were linked to a large pharmaceutical claims warehouse (2007-2015) to characterize prescription opioid use before and after kidney transplant, and associations (adjusted hazard ratio,

Indexed as

Graft SurvivalAdolescentAdultAnalgesics, OpioidDelayed Graft FunctionFemaleFollow-Up StudiesGraft RejectionHumansKidney Failure, ChronicKidney TransplantationMaleMiddle AgedOpioid-Related DisordersPostoperative ComplicationsPrognosisAnalgesics, Opioidclinical research/practiceepidemiologykidney transplantation/nephrologyScientific Registry for Transplant Recipients (SRTR)

Identifiers

PMID29498196
PMCPMC6119653

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.