Evidence map›Paper›PMID 29498170›Full record

Trial reportAddiction biology2019

Pharmacogenetics of Dopamine β-Hydroxylase in cocaine dependence therapy with doxazosin.

Xuefeng Zhang, David A Nielsen, Coreen B Domingo, Daryl I Shorter, Ellen M Nielsen, Thomas R Kosten

Open access · greenAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Addiction biology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.5field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 20 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Review
  6. Pharmacogenetics of Addiction Therapy.Methods in molecular biology (Clifton, N.J.) · 2022
    Article
  7. Review
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Xuefeng ZhangMichael E. DeBakey Veterans Affairs Medical Center, Houston, TX, USA.ORCID 0000-0002-9676-6136
David A NielsenMichael E. DeBakey Veterans Affairs Medical Center, Houston, TX, USA.
Coreen B DomingoMichael E. DeBakey Veterans Affairs Medical Center, Houston, TX, USA.
Daryl I ShorterMichael E. DeBakey Veterans Affairs Medical Center, Houston, TX, USA.
Ellen M NielsenMichael E. DeBakey Veterans Affairs Medical Center, Houston, TX, USA.
Thomas R KostenMichael E. DeBakey Veterans Affairs Medical Center, Houston, TX, USA.
Michael E. DeBakey VA Medical Center · US

Funding

Tiagabine and Disulfiram for Cocaine DependenceP50DA018197 · NIDA · YALE UNIVERSITY · PI KOSTEN, THOMAS RICHARD · 2004 to 2013
$12.6M
Michael E. DeBakey VA Medical CenterNIDA NIH HHS N01 DA018827NIDA NIH HHS P50 DA018197The Toomim Family Fund
6 · The paper itself

Abstract

The α

Indexed as

Adrenergic alpha-1 Receptor AntagonistsCocaine-Related DisordersDopamine beta-HydroxylaseDouble-Blind MethodDoxazosinFemaleGenotypeHumansMaleMiddle AgedNorepinephrinePolymorphism, GeneticTreatment OutcomeAdrenergic alpha-1 Receptor AntagonistsDopamine beta-HydroxylaseDoxazosinNorepinephrine

Identifiers

PMID29498170
PMCPMC6119656
OpenAlexW2790553980

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.