ArticleJournal of clinical laboratory analysis2018
The CDKN2A polymorphisms and the susceptibility of HBV-related gestational diabetes mellitus.
Article in Journal of clinical laboratory analysis, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed, 4 citations in OpenAlex.
- Hepatitis B virus infection, infertility, and assisted reproduction.Journal of Zhejiang University. Science. B · 2024Review
- System Biology Investigation Revealed Lipopolysaccharide and Alcohol-Induced Hepatocellular Carcinoma Resembled Hepatitis B Virus Immunobiology and Pathogenesis.International journal of molecular sciences · 2023Article
- The lncRNAJournal of inflammation research · 2021Article
- The CDKN2A polymorphisms and the susceptibility of HBV-related gestational diabetes mellitus.Journal of clinical laboratory analysis · 2018Article
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
Abstract
backgroundSingle-nucleotide polymorphisms (SNPs) were discovered in HBV-related gestational diabetes mellitus, but it still unclear whether these SNPs are associated with the susceptibility of HBV-related gestational diabetes mellitus.
methodsThe investigation of the association between CDKN2A polymorphisms and occurrence of HBV-related gestational diabetes mellitus (GDM) in Chinese was assessed in the case-control study. A total of 480 pregnant patients with HBV and 530 pregnant controls were consecutively recruited from January 2015 to December 2016. Polymerase chain reaction-restriction fragment length polymorphisms (PCR-RFLP) method was applied to measure genotyping for the detection of CDKN2A.
resultsThe significant differences in the frequency of CDKN2A genotype distributions, rs10811661 and rs564398, were found by Chi-square test. Using conditional logistic analysis, individuals carrying the CDKN2A rs10811661 TC and TT genotypes and CDKN2A rs564398 AA and AG genotypes were related to a greater risk of HBV-related GDM compared with the genotype.
conclusionsIn conclusion, the CDKN2A rs10811661 and rs564398 polymorphisms showed association with a greater risk of HBV-related GDM in a Chinese population.
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