ArticleFolia microbiologica2018
Bioprospecting of Diaporthe terebinthifolii LGMF907 for antimicrobial compounds.
Article in Folia microbiologica, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed.
- Antimicrobial Compounds FromInternational journal of microbiology · 2025Article
- Physiological mechanism of action and partial separation of herbicide-active compounds from the Diaporthe sp. extract on Amaranthus tricolor L.Scientific reports · 2023Article
- Beyond Penicillin: The Potential of Filamentous Fungi for Drug Discovery in the Age of Antibiotic Resistance.Antibiotics (Basel, Switzerland) · 2023Review
- Potential of Secondary Metabolites ofJournal of fungi (Basel, Switzerland) · 2023Review
- Endophytic Fungi as a Source of Antibacterial Compounds-A Focus on Gram-Negative Bacteria.Antibiotics (Basel, Switzerland) · 2022Review
- Antimicrobial potentials of natural products against multidrug resistance pathogens: a comprehensive review.RSC advances · 2022Review
- Fungal Endophytes: A Potential Source of Antibacterial Compounds.Journal of fungi (Basel, Switzerland) · 2022Review
- Bioactive Secondary Metabolites of the GenusMicroorganisms · 2021Review
- Chemical Diversity of Secondary Metabolites Produced by Brazilian Endophytic Fungi.Current microbiology · 2021Review
- Diversity, Chemical Constituents and Biological Activities of Endophytic Fungi Isolated fromMicroorganisms · 2020Article
- Dihydroisocoumarins produced by Diaporthe cf. heveae LGMF1631 inhibiting citrus pathogens.Folia microbiologica · 2020Article
- Vochysiamides A and B: Two new bioactive carboxamides produced by the new species Diaporthe vochysiae.Fitoterapia · 2019Article
Corrections and comments
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Authors and funding
8 authors.
Funding
Abstract
Antibiotic-resistant bacteria have been observed with increasing frequency over the past decades, driving the search for new drugs and stimulating the interest in natural products sources. Endophytic fungi from medicinal plants represent a great source of novel bioactive compounds useful to pharmaceutical and agronomical purposes. Diaporthe terebinthifolii is an endophytic species isolated from Schinus terebinthifolius, a plant used in popular medicine for several health problems. The strain D. terebinthifolii LGMF907 was previously reported by our group to produce secondary metabolites with biological activity against phytopathogens. Based on these data, strain LGMF907 was chosen for bioprospecting against microorganisms of clinical importance and for characterization of major secondary metabolites. In this study, different culture conditions were evaluated and the biological activity of this strain was expanded. The crude extracts demonstrated high antibacterial activity against Escherichia coli, Micrococcus luteus, Saccharomyces cerevisiae, methicillin-sensitive Staphylococcus aureus, and methicillin-resistant S. aureus. The compounds diaporthin and orthosporin were characterized and also showed activity against the clinical microorganisms evaluated. This study discloses the first isolation of diaporthin and orthosporin from D. terebinthifolii, and revealed the potential of this endophytic fungus to produce secondary metabolites with antimicrobial activity.
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