Evidence map›Paper›PMID 29497887›Full record

ArticleClinical autonomic research : official journal of the Clinical Autonomic Research Society2018

Autonomic symptoms following Zika virus infection.

Yhojan Rodríguez, Manuel Rojas, Carolina Ramírez-Santana, Yeny Acosta-Ampudia, Diana M Monsalve, Juan-Manuel Anaya

Open access · greenAbstract read
PubMed Publisher
In one paragraph

Article in Clinical autonomic research : official journal of the Clinical Autonomic Research Society, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 13 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Comment on: Zika virus and Guillain-Barré syndrome in Bangladesh.Annals of clinical and translational neurology · 2018
    Article
  5. Autonomic dysfunction: a novel neurological phenotype associated with Zika virus infection?Clinical autonomic research : official journal of the Clinical Autonomic Research Society · 2018
    Article
  6. Zika virus infection and autonomic symptoms.Clinical autonomic research : official journal of the Clinical Autonomic Research Society · 2018
    Article
  7. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Yhojan RodríguezCenter for Autoimmune Diseases Research (CREA), School of Medicine and Health Sciences, Universidad del Rosario, Carrera 26-63-B-51, 110010, Bogotá, Colombia.
Manuel RojasCenter for Autoimmune Diseases Research (CREA), School of Medicine and Health Sciences, Universidad del Rosario, Carrera 26-63-B-51, 110010, Bogotá, Colombia.
Carolina Ramírez-SantanaCenter for Autoimmune Diseases Research (CREA), School of Medicine and Health Sciences, Universidad del Rosario, Carrera 26-63-B-51, 110010, Bogotá, Colombia.
Yeny Acosta-AmpudiaCenter for Autoimmune Diseases Research (CREA), School of Medicine and Health Sciences, Universidad del Rosario, Carrera 26-63-B-51, 110010, Bogotá, Colombia.
Diana M MonsalveCenter for Autoimmune Diseases Research (CREA), School of Medicine and Health Sciences, Universidad del Rosario, Carrera 26-63-B-51, 110010, Bogotá, Colombia.
Juan-Manuel AnayaCenter for Autoimmune Diseases Research (CREA), School of Medicine and Health Sciences, Universidad del Rosario, Carrera 26-63-B-51, 110010, Bogotá, Colombia. juan.anaya@urosario.edu.co.ORCID http://orcid.org/0000-0002-6444-1249
Universidad del Rosario · CO

Funding

Departamento Administrativo de Ciencia, Tecnología e Innovación 747-2016Universidad del Rosario ABN011
6 · The paper itself

Abstract

purposeTo determine if autonomic symptoms are associated with previous Zika virus infection.

methodsCase-control study including 35 patients with Zika virus infection without evidence of neurological disease and 105 controls. Symptoms of autonomic dysfunction were assessed with the composite autonomic symptom scale 31 (COMPASS-31).

resultsPatients with previous Zika virus infection had significantly higher COMPASS-31 score than controls regardless of age and sex (p = 0.007). The main drivers for the higher scores where orthostatic intolerance (p = 0.003), secretomotor (p = 0.04) and bladder symptoms (p < 0.001).

conclusionZika virus infection is associated with autonomic dysfunction. The mechanisms remain to be elucidated.

Indexed as

AdultAutonomic Nervous System DiseasesCase-Control StudiesFemaleHumansMaleMiddle AgedRetrospective StudiesZika Virus InfectionAutonomic symptomsCOMPASS 31DysautonomiaFlavivirusZika virus

Identifiers

PMID29497887
OpenAlexW2793644763

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.