ArticleThe Analyst2018
Infrared ion spectroscopy: an analytical tool for the study of metabolites.
Article in The Analyst, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
14 citing papers in PubMed.
- Infrared Photodissociation Spectroscopy of Water-Tagged Ions with a Widely Tunable Quantum Cascade Laser for Planetary Science Applications.Analytical chemistry · 2024Article
- Structural Elucidation of Agrochemical Metabolic Transformation Products Based on Infrared Ion Spectroscopy to Improve In Silico Toxicity Assessment.Chemical research in toxicology · 2024Article
- Protonated Forms of Naringenin and Naringenin Chalcone: Proteiform Bioactive Species Elucidated by IRMPD Spectroscopy, IMS, CID-MS, and Computational Approaches.Journal of agricultural and food chemistry · 2023Article
- Binding Modes of a Cytotoxic Dinuclear Copper(II) Complex with Phosphate Ligands Probed by Vibrational Photodissociation Ion Spectroscopy.Inorganic chemistry · 2023Article
- Differentiation between Isomeric 4,5-Functionalized 1,2,3-Thiadiazoles and 1,2,3-Triazoles by ESI-HRMS and IR Ion Spectroscopy.Molecules (Basel, Switzerland) · 2023Article
- Article
- Infrared multiple photon dissociation (IRMPD) spectroscopy and its potential for the clinical laboratory.Journal of mass spectrometry and advances in the clinical lab · 2022Article
- Metabolite Identification Using Infrared Ion Spectroscopy─Novel Biomarkers for Pyridoxine-Dependent Epilepsy.Analytical chemistry · 2021Article
- Evaluation of table-top lasers for routine infrared ion spectroscopy in the analytical laboratory.The Analyst · 2021Article
- Quantum Chemistry Calculations for Metabolomics.Chemical reviews · 2021Review
- Molecular Properties of Bare and Microhydrated Vitamin B5-Calcium Complexes.International journal of molecular sciences · 2021Article
- Mass-Spectrometry-Based Identification of Synthetic Drug Isomers Using Infrared Ion Spectroscopy.Analytical chemistry · 2020Article
- Gas-Phase Infrared Spectroscopy of Neutral Peptides: Insights from the Far-IR and THz Domain.Chemical reviews · 2020Review
- Operation and Performance of a Mass-Selective Cryogenic Linear Ion Trap.Journal of the American Society for Mass Spectrometry · 2018Article
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
Vibrational ion spectroscopy techniques coupled with mass spectrometry are applied to standard metabolites as a proof-of-principle demonstration for the structural identification of unknown metabolites. The traditional room temperature infrared multiple photon dissociation (IRMPD) spectroscopy technique is shown to differentiate chemical moieties in isobaric and isomeric variants. These results are compared to infrared spectra of cryogenically cooled analyte ions, showing enhanced spectral resolution, and thus also improved differentiation between closely related molecules, such as isomers. The cryogenic spectroscopy is effected in a recently developed mass-selective cryogenic linear ion trap, which is capable of high sensitivity and the ability to measure the IR spectra of multiple analytes simultaneously.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.