Evidence map›Paper›PMID 29497581›Full record

ArticleTranslational vision science & technology2018

Detecting Glaucomatous Progression With a Region-of-Interest Approach on Optical Coherence Tomography: A Signal-to-Noise Evaluation.

Zhichao Wu, Abinaya Thenappan, Denis S D Weng, Robert Ritch, Donald C Hood

Abstract read
In one paragraph

Article in Translational vision science & technology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Zhichao WuDepartment of Psychology, Columbia University, New York, NY, USA.
Abinaya ThenappanDepartment of Psychology, Columbia University, New York, NY, USA.
Denis S D WengDepartment of Psychology, Columbia University, New York, NY, USA.
Robert RitchEinhorn Clinical Research Center, New York Eye and Ear Infirmary of Mount Sinai, New York, NY, USA.
Donald C HoodDepartment of Psychology, Columbia University, New York, NY, USA.

Funding

Tests of Models of Retinal/Optic Nerve Diseases&AdaptionR01EY002115 · NEI · COLUMBIA UNIV NEW YORK MORNINGSIDE · PI HOOD, DONALD C. · 1985 to 2018
$7.4M
The Brief Research in Aging and Interdisciplinary NeurosciencesT35AG044303 · NIA · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI Sachin Agarwal, Jennifer Jaie Manly · 2013 to 2026
$1.9M
NEI NIH HHS R01 EY002115
6 · The paper itself

Abstract

purposeTo compare two region-of-interest (ROI) approaches and a global thickness approach for capturing progressive circumpapillary retinal nerve fiber layer (cpRNFL) changes on optical coherence tomography (OCT) imaging.

methodsProgressive cpRNFL thickness changes were evaluated in 164 eyes with a clinical diagnosis of glaucoma or suspected glaucoma; all eyes underwent optic disc OCT imaging on two visits at least 1 year apart. Such changes were evaluated with a manual ROI approach (ROI

resultsThe average longitudinal SNR of the ROI

conclusionsA manual ROI approach was the optimal method for detecting progressive cpRNFL loss compared with an automatic ROI approach and the global cpRNFL thickness measure. TRANSLATIONAL RELEVANCE: These findings highlight the potential advantages conferred by a careful qualitative evaluation of OCT imaging for detecting glaucoma progression.

Indexed as

glaucomaoptical coherence tomographyprogressionregion-of-interest

Identifiers

PMID29497581
PMCPMC5829954

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LicenceCC BY-NC-ND
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.