Evidence map›Paper›PMID 29497502›Full record

SynthesisJournal of global health2018

Association of obstructive sleep apnea with hypertension: A systematic review and meta-analysis.

Haifeng Hou, Yange Zhao, Wenqing Yu, Hualei Dong, Xiaotong Xue, Jian Ding, Weijia Xing, Wei Wang

Open access · goldAbstract readMeta-AnalysisSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Journal of global health, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 162 papers, 19 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
162citing papers in PubMed, 19 pooled it
15.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

162 citing papers in PubMed, 19 syntheses or guidelines pooled it, 335 citations in OpenAlex.

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  6. A Systematic Review of Publications on the Associations Between Sleep Architecture and Arterial Hypertension.Medical science monitor : international medical journal of experimental and clinical research · 2023
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  10. Effects of Exercise on Patients with Obstructive Sleep Apnea: A Systematic Review and Meta-Analysis.International journal of environmental research and public health · 2022
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  11. Cardiac consequences of intermittent hypoxia: a matter of dose? A systematic review and meta-analysis in rodents.European respiratory review : an official journal of the European Respiratory Society · 2022
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102 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Haifeng HouSchool of Public Health, Taishan Medical University, Taian, China.
Yange ZhaoSchool of Basic Medical Science, Taishan Medical University, Taian, China.
Wenqing YuSchool of Basic Medical Science, Taishan Medical University, Taian, China.
Hualei DongTaishan Hospital of Shandong Province, Taian, China.
Xiaotong XueTaishan Hospital of Shandong Province, Taian, China.
Jian DingTaishan Hospital of Shandong Province, Taian, China.
Weijia XingSchool of Public Health, Taishan Medical University, Taian, China.
Wei WangSchool of Public Health, Taishan Medical University, Taian, China.
Affiliated Hospital of Taishan Medical University · CNTaishan Medical University · CNEdith Cowan University · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundObstructive sleep apnea (OSA) is a sleep disorder characterized as complete or partial upper airflow cessation during sleep. Although it has been widely accepted that OSA is a risk factor for the development of hypertension, the studies focusing on this topic revealed inconsistent results. We aimed to clarify the association between OSA and hypertension, including essential and medication-resistant hypertension.

methodsThe Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) was followed. PubMed and Embase databases were used for searching the relevant studies published up to December 31, 2016. A quantitative approach of meta-analysis was performed to estimate the pooled odds ratio (OR) and 95% confidence interval (CI).

resultsTwenty-six studies with 51 623 participants (28 314 men, 23 309 women; mean age 51.8 years) met inclusion criteria and were included in this study. Among them, six studies showed a significant association between OSA and resistant hypertension (pooled OR = 2.842, 95% CI = 1.703-3.980,

conclusionsOur findings indicated that OSA is related to an increased risk of resistant hypertension. Mild, moderate and severe OSA are associated essential hypertension, as well a dose-response manner relationship is manifested. The associations are relatively stronger among Caucasians and male OSA patients.

Indexed as

HumansHypertensionRisk FactorsSleep Apnea, Obstructive

Identifiers

PMID29497502
PMCPMC5825975
OpenAlexW2786362430

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.