ArticleFrontiers in psychiatry2018
Psychosocial Variables Associated with Immunosuppressive Medication Non-Adherence after Renal Transplantation.
Article in Frontiers in psychiatry, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 1 of them a synthesis that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
26 citing papers in PubMed, 1 synthesis or guideline pooled it, 38 citations in OpenAlex.
- Psychological factors associated with medication non-adherence after kidney transplant: a systematic review.BMC psychology · 2026Pooled it
- Two-Year Follow-Up of a Communication Intervention on Medication Adherence and Health Literacy in Kidney Transplanted Recipients-A Randomised Controlled Study.Journal of renal care · 2025Trial
- Impact of a Mobile Health Intervention on Long-term Nonadherence After Lung Transplantation: Follow-up After a Randomized Controlled Trial.Transplantation · 2020Trial
- Do we Treat the Right Patients? Predictors of Psychosocial Treatment Frequencies in a Multimodal Aftercare Program: A KTx360° Substudy.Transplantation direct · 2026Article
- Longitudinal Course and Baseline Predictors of Trajectories of Clinician-assessed Adherence to Immunosuppressant Medication in Patients after Kidney Transplantation: A KTx360° Substudy.Transplantation direct · 2025Article
- Predictors of Treatment Adherence in Kidney Transplant Patients: A Systematic Review of the Literature.Journal of clinical medicine · 2025Review
- SELF-REPORTED QUALITY OF LIFE, IMPULSIVITY AND NON-ADHERENCE TO IMMUNOSUPPRESSIVE MEDICATION AFTER LIVER TRANSPLANTATION: A COHORT STUDY.Arquivos de gastroenterologia · 2025Article
- Transition of care from pediatric to adult nephrology post-renal transplant: a review.Translational pediatrics · 2024Review
- Immunosuppressant Adherence Factors Differentiating Compliant and Non-Compliant Kidney Transplant Recipients.Journal of clinical medicine · 2023Article
- Sickness Symptoms in Kidney Transplant Recipients: A Scoping Review.Western journal of nursing research · 2023Article
- Quality of life associated with immunosuppressant treatment adherence in liver transplant recipients: A cross-sectional study.Frontiers in pharmacology · 2023Article
- Prevalence and Patient-Level Correlates of Intentional Non-Adherence to Immunosuppressive Medication After Heart-Transplantation-Findings From the International BRIGHT Study.Transplant international : official journal of the European Society for Organ Transplantation · 2023Article
- Sex-specific time trends of long-term graft survival after kidney transplantation - a registry-based study.Renal failure · 2023Article
- Prevalence and Modifiable Factors for Holistic Non-Adherence in Renal Transplant Patients: A Cross-Sectional Study.Patient preference and adherence · 2023Article
- [Long-term physical and psychological consequences of chronic kidney disease].Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz · 2022Review
- Adherence to Immunosuppressive Therapies after Kidney Transplantation from a Biopsychosocial Perspective: A Cross-Sectional Study.Journal of clinical medicine · 2022Article
- Depression, Quantified Medication Adherence, and Quality of Life in Renal Transplant Candidates and Recipients.Journal of clinical psychology in medical settings · 2022Article
- Medication, Healthcare Follow-up, and Lifestyle Nonadherence: Do They Share the Same Risk Factors?Transplantation direct · 2022Article
- Follow-Up Factors Contribute to Immunosuppressant Adherence in Kidney Transplant Recipients.Patient preference and adherence · 2022Article
- Applying A Biopsychosocial Framework to Achieve Durable Behavior Change in Kidney Disease.Seminars in nephrology · 2021Review
Corrections and comments
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Authors and funding
12 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionNon-adherence to immunosuppressive medication is regarded as an important factor for graft rejection and loss after successful renal transplantation. Yet, results on prevalence and relationship with psychosocial parameters are heterogeneous. The main aim of this study was to investigate the association of immunosuppressive medication non-adherence and psychosocial factors.
methodsIn 330 adult renal transplant recipients (≥12 months posttransplantation), health-related quality of life, depression, anxiety, social support, and subjective medication experiences were assessed, and their associations with patient-reported non-adherence was evaluated.
results33.6% of the patients admitted to be partially non-adherent. Non-adherence was associated with younger age, poorer social support, lower mental, but higher physical health-related quality of life. There was no association with depression and anxiety. However, high proportions of clinically relevant depression and anxiety symptoms were apparent in both adherent and non-adherent patients.
conclusionIn the posttransplant follow-up, kidney recipients with lower perceived social support, lower mental and higher physical health-related quality of life, and younger age can be regarded as a risk group for immunosuppressive medication non-adherence. In follow-up contacts with kidney transplant patients, physicians may pay attention to these factors. Furthermore, psychosocial interventions to optimize immunosuppressive medication adherence can be designed on the basis of this information, especially including subjectively perceived physical health-related quality of life and fostering social support seems to be of importance.
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