Evidence map›Paper›PMID 29497293›Full record

ArticleInternational journal of nanomedicine2018

Tannic acid-modified silver nanoparticles for wound healing: the importance of size.

Piotr Orlowski, Magdalena Zmigrodzka, Emilia Tomaszewska, Katarzyna Ranoszek-Soliwoda, Monika Czupryn, Malgorzata Antos-Bielska, Janusz Szemraj, Grzegorz Celichowski, Jaroslaw Grobelny, Malgorzata Krzyzowska

Abstract read
In one paragraph

Article in International journal of nanomedicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 57 papers.

0numbers the graph read from it
0cells of the map it votes in
57citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

57 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Piotr OrlowskiMilitary Institute of Hygiene and Epidemiology, Warsaw, Poland.
Magdalena ZmigrodzkaDepartment of Pathology and Veterinary Diagnostics, Faculty of Veterinary Medicine, Warsaw University of Life Sciences (WULS-SGGW), Warsaw, Poland.
Emilia TomaszewskaDepartment of Materials Technology and Chemistry, Faculty of Chemistry, University of Lodz, Lodz, Poland.
Katarzyna Ranoszek-SoliwodaDepartment of Materials Technology and Chemistry, Faculty of Chemistry, University of Lodz, Lodz, Poland.
Monika CzuprynMilitary Institute of Hygiene and Epidemiology, Warsaw, Poland.
Malgorzata Antos-BielskaMilitary Institute of Hygiene and Epidemiology, Warsaw, Poland.
Janusz SzemrajBionanopark, Lodz, Poland.
Grzegorz CelichowskiDepartment of Materials Technology and Chemistry, Faculty of Chemistry, University of Lodz, Lodz, Poland.
Jaroslaw GrobelnyDepartment of Materials Technology and Chemistry, Faculty of Chemistry, University of Lodz, Lodz, Poland.
Malgorzata KrzyzowskaMilitary Institute of Hygiene and Epidemiology, Warsaw, Poland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionSilver nanoparticles (AgNPs) have been shown to promote wound healing and to exhibit antimicrobial properties against a broad range of bacteria. In our previous study, we prepared tannic acid (TA)-modified AgNPs showing a good toxicological profile and immunomodulatory properties useful for potential dermal applications.

methodsIn this study, in vitro scratch assay, antimicrobial tests, modified lymph node assay as well as a mouse splint wound model were used to access the wound healing potential of TA-modified and unmodified AgNPs.

resultsTA-modified but not unmodified AgNPs exhibited effective antibacterial activity against

conclusionTA-modified AgNPs sized >26 nm promote wound healing better than TA-modified or unmodified AgNPs. These findings suggest that TA-modified AgNPs sized >26 nm may have a promising application in wound management.

Indexed as

Particle SizeWound HealingAnimalsAnti-Bacterial AgentsBacteriaCell LineCytokinesDermisDisease Models, AnimalDynamic Light ScatteringEndocytosisFemaleFibroblastsHumansInflammationKeratinocytesAnti-Bacterial AgentsCytokinesSilverTanninsantimicrobialsfibroblastshydrolyzable tannininflammationmonocytessilversplit wound

Identifiers

PMID29497293
PMCPMC5818815

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.