Evidence map›Paper›PMID 29497168›Full record

ArticleScientific reports2018

Analysis of (CAG)

X Zhou, C Wang, D Ding, Z Chen, Y Peng, H Peng, X Hou, P Wang, X Hou, W Ye and 7 more

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.6field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 13 citations in OpenAlex.

  1. Review
  2. The genetic basis of multiple system atrophy.Journal of translational medicine · 2023
    Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 2 institutions in 2 countries.

X ZhouDepartment of Neurology, Xiangya Hospital, Central South University, Changsha, Hunan, 410008, P. R. China.
C WangDepartment of Neurology, Xiangya Hospital, Central South University, Changsha, Hunan, 410008, P. R. China.
D DingDepartment of Neurology, Xiangya Hospital, Central South University, Changsha, Hunan, 410008, P. R. China.
Z ChenDepartment of Neurology, Xiangya Hospital, Central South University, Changsha, Hunan, 410008, P. R. China.
Y PengDepartment of Neurology, Xiangya Hospital, Central South University, Changsha, Hunan, 410008, P. R. China.
H PengDepartment of Neurology, Xiangya Hospital, Central South University, Changsha, Hunan, 410008, P. R. China.
X HouDepartment of Neurology, Xiangya Hospital, Central South University, Changsha, Hunan, 410008, P. R. China.
P WangDepartment of Neurology, Xiangya Hospital, Central South University, Changsha, Hunan, 410008, P. R. China.
X HouDepartment of Neurology, Xiangya Hospital, Central South University, Changsha, Hunan, 410008, P. R. China.
W YeDepartment of Neurology, Xiangya Hospital, Central South University, Changsha, Hunan, 410008, P. R. China.
T LiDepartment of Neurology, Xiangya Hospital, Central South University, Changsha, Hunan, 410008, P. R. China.
H YangDepartment of Neurology, Xiangya Hospital, Central South University, Changsha, Hunan, 410008, P. R. China.
R QiuSchool of Information Science and Engineering, Central South University, Changsha, Hunan, 410083, P. R. China.
K XiaLaboratory of Medical Genetics, Central South University, Changsha, Hunan, 410078, P. R. China.
J SequeirosIBMC - Institute for Molecular and Cell Biology, i3S - Instituto de Investigação e Inovação na Saúde; and ICBAS; Univ. Porto, Porto, Portugal.ORCID 0000-0002-9846-1037
B TangDepartment of Neurology, Xiangya Hospital, Central South University, Changsha, Hunan, 410008, P. R. China.
H JiangDepartment of Neurology, Xiangya Hospital, Central South University, Changsha, Hunan, 410008, P. R. China. jianghong73868@126.com.
Central South University · CNUniversidade Sénior Contemporânea · PT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Multiple system atrophy (MSA) is a complex and multifactorial neurodegenerative disease, and its pathogenesis remains uncertain. Patients with MSA or spinocerebellar ataxia (SCA) show overlapping clinical phenotypes. Previous studies have reported that intermediate or long CAG expansions in SCA genes have been associated with other neurodegenerative disease. In this study, we screened for the number of CAG repeats in ATXN1, 2 and 3 in 200 patients with MSA and 314 healthy controls to evaluate possible associations between (CAG)

Indexed as

AdultAgedAge of OnsetAsian PeopleAtaxin-1Ataxin-2Ataxin-3AtaxinsChinaFemaleGene FrequencyHumansMaleMiddle AgedMultiple System AtrophyNerve Tissue ProteinsAtaxin-1Ataxin-2Ataxin-3AtaxinsATXN1 protein, humanATXN2 protein, humanATXN3 protein, humanNerve Tissue ProteinsRepressor Proteins

Identifiers

PMID29497168
PMCPMC5832826
OpenAlexW2806816982

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.