ArticleScientific reports2018
Preoperative Heart Rate Variability as Predictors of Vagus Nerve Stimulation Outcome in Patients with Drug-resistant Epilepsy.
Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed.
- Digital Cardiovascular Biomarker Responses to Transcutaneous Cervical Vagus Nerve Stimulation: State-Space Modeling, Prediction, and Simulation.JMIR mHealth and uHealth · 2020Trial
- Effects of non-invasive trigeminal nerve stimulation frequency and duration on cardiovascular responses.Biomedical engineering letters · 2026Article
- Introducing the Index of Response to Stimulation (IRES): A Novel Metric for Assessing Vagus Nerve Stimulation Outcomes in Drug-Resistant Epilepsy.Medicina (Kaunas, Lithuania) · 2025Article
- Vagus nerve stimulation for epilepsy: A narrative review of factors predictive of response.Epilepsia · 2024Review
- Research progress on the electrophysiological indicators to predict the efficacy of vagus nerve stimulation for drug-refractory epilepsy.Acta epileptologica · 2024Review
- Effects of vagal nerve stimulation parameters on heart rate variability in epilepsy patients.Frontiers in neurology · 2024Article
- Predictive factors for successful vagus nerve stimulation in patients with refractory epilepsy: real-life insights from a multicenter study.Frontiers in neuroscience · 2023Article
- Article
- Vagus nerve stimulation for refractory posttraumatic epilepsy: Efficacy and predictors of seizure outcome.Frontiers in neurology · 2022Article
- Effectiveness of vagus nerve stimulation therapy in refractory hypoxic-ischemic encephalopathy-induced epilepsy.Therapeutic advances in neurological disorders · 2022Article
- Vagus nerve stimulation for pharmacoresistant epilepsy secondary to encephalomalacia: A single-center retrospective study.Frontiers in neurology · 2022Article
- Altered Relationship Between Heart Rate Variability and fMRI-Based Functional Connectivity in People With Epilepsy.Frontiers in neurology · 2021Article
- Preoperative Heart Rate Variability During Sleep Predicts Vagus Nerve Stimulation Outcome Better in Patients With Drug-Resistant Epilepsy.Frontiers in neurology · 2021Article
- Brain Functional Mechanisms Determining the Efficacy of Transcutaneous Auricular Vagus Nerve Stimulation in Primary Insomnia.Frontiers in neuroscience · 2021Article
- [Application of scalp electroencephalogram in treatment of refractory epilepsy with vagus nerve stimulation].Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi · 2020Review
- Vagus Nerve Stimulation at the Interface of Brain-Gut Interactions.Cold Spring Harbor perspectives in medicine · 2019Review
- On the Robustness of Multiscale Indices for Long-Term Monitoring in Cardiac Signals.Entropy (Basel, Switzerland) · 2019Article
- Sign and magnitude scaling properties of heart rate fluctuations following vagus nerve stimulation in a patient with drug-resistant epilepsy.Epilepsy & behavior case reports · 2018Article
- Neurostimulation as a Putative Method for the Treatment of Drug-resistant Epilepsy in Patient and Animal Models of Epilepsy.Basic and clinical neuroscienceReview
- Neuromodulation for Refractory Epilepsy.Epilepsy currentsArticle
Corrections and comments
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Authors and funding
14 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Vagus nerve stimulation (VNS) is an adjunctive treatment for drug-resistant epilepsy (DRE). However, it is still difficult to predict which patients will respond to VNS treatment and to what extent. We aim to explore the relationship between preoperative heart rate variability (HRV) and VNS outcome. 50 healthy control subjects and 63 DRE patients who had received VNS implants and had at least one year of follow up were included. The preoperative HRV were analyzed by traditional linear methods and heart rhythm complexity analyses with multiscale entropy (MSE). DRE patients had significantly lower complexity indices (CI) as well as traditional linear HRV measurements than healthy controls. We also found that non-responders
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