Evidence map›Paper›PMID 29497045›Full record

ArticleScientific reports2018

Preparation and Imaging Investigation of Dual-targeted C

Jing Du, Xiao-Yu Li, He Hu, Li Xu, Shi-Ping Yang, Feng-Hua Li

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
2.7field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 50 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Article
  6. Molecular Imaging for Early-Stage Disease Diagnosis.Advances in experimental medicine and biology · 2023
    Article
  7. Review
  8. Review
  9. Article
  10. Molecular Ultrasound Imaging.Nanomaterials (Basel, Switzerland) · 2020
    Review
  11. Article
  12. Bulk Nanobubbles or Not Nanobubbles: That is the Question.Langmuir : the ACS journal of surfaces and colloids · 2020
    Article
  13. The Design of Poly(lactide-co-glycolide) Nanocarriers for Medical Applications.Frontiers in bioengineering and biotechnology · 2020
    Review
  14. Article
  15. Article
  16. Article
  17. Nanobubble Contrast Enhanced Ultrasound Imaging: A Review.Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology
    Review
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Jing DuDepartment of Ultrasound, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, 160 Pu Jian Rd, Shanghai, 200127, China.
Xiao-Yu LiDepartment of Ultrasound, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, 160 Pu Jian Rd, Shanghai, 200127, China.
He HuDepartment of Biomedical Engineering, Case Western Reserve University Schools of Medicine, 10900 Euclid Ave., Cleveland, OH, 44106, USA.ORCID 0000-0002-5976-5273
Li XuDepartment of Ultrasound, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, 160 Pu Jian Rd, Shanghai, 200127, China.
Shi-Ping YangDepartment of Chemistry, Shanghai Normal University, 100 Gui Lin Rd, Shanghai, 200234, China. fenghua-li@163.com.
Feng-Hua LiDepartment of Ultrasound, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, 160 Pu Jian Rd, Shanghai, 200127, China. shipingy@shnu.edu.cn.
Shanghai Jiao Tong University · CNShanghai Normal University · CNUniversity School · US

Funding

EPA EP-C-17-015
6 · The paper itself

Abstract

Molecularly-targeted contrast enhanced ultrasound (US) imaging is a promising imaging strategy with large potential for improving diagnostic accuracy of conventional US imaging in breast cancer detection. Therefore, we constructed a novel dual-targeted nanosized US contrast agent (UCA) directed at both vascular endothelial growth factor receptor 2 (VEGFR2) and human epidermal growth factor receptor 2 (HER2) based on perfluoropropane (C

Indexed as

AnimalsBreast NeoplasmsCell Line, TumorContrast MediaErb-b2 Receptor Tyrosine KinasesFemaleFluorocarbonsHumansLactic AcidMiceMice, Inbred BALB CMice, NudeMicrobubblesMolecular ImagingPolyglycolic AcidPolylactic Acid-Polyglycolic Acid CopolymerContrast MediaERBB2 protein, humanErb-b2 Receptor Tyrosine KinasesFluorocarbonsKDR protein, humanLactic AcidperflutrenPolyglycolic AcidPolylactic Acid-Polyglycolic Acid CopolymerVascular Endothelial Growth Factor AVascular Endothelial Growth Factor Receptor-2

Identifiers

PMID29497045
PMCPMC5832866
OpenAlexW2806533169

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.