Evidence map›Paper›PMID 29496982›Full record

ArticleJournal of nuclear medicine : official publication, Society of Nuclear Medicine2018

Joint Reconstruction of Activity and Attenuation in Time-of-Flight PET: A Quantitative Analysis.

Ahmadreza Rezaei, Christophe M Deroose, Thomas Vahle, Fernando Boada, Johan Nuyts

Abstract read
In one paragraph

Article in Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed.

  1. Eagle eyes on the human brain and beyond: PET at ultra-high spatial resolution.European journal of nuclear medicine and molecular imaging · 2026
    Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Synthetic PET via Domain Translation of 3-D MRI.IEEE transactions on radiation and plasma medical sciences · 2023
    Article
  8. Article
  9. Deep learning-based attenuation correction for whole-body PET - a multi-tracer study withEuropean journal of nuclear medicine and molecular imaging · 2022
    Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. Quantitative PET in the 2020s: a roadmap.Physics in medicine and biology · 2021
    Article
  16. Article
  17. Deep-JASC: joint attenuation and scatter correction in whole-bodyEuropean journal of nuclear medicine and molecular imaging · 2020
    Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Ahmadreza RezaeiNuclear Medicine and Molecular Imaging, KU Leuven, Leuven, Belgium ahmadreza.rezaei@uz.kuleuven.be.
Christophe M DerooseNuclear Medicine and Molecular Imaging, KU Leuven, Leuven, Belgium.
Thomas VahleSiemens Healthcare GmbH, Erlangen, Germany; and.
Fernando BoadaNew York University Medical Center, New York, New York.
Johan NuytsNuclear Medicine and Molecular Imaging, KU Leuven, Leuven, Belgium.

Funding

TR&D 4: Revealing Microstructure: Biophysical modeling and validation for discovery and clinical careP41EB017183 · NIBIB · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI Christopher M Collins · 2014 to 2026
$19.3M
NIBIB NIH HHS P41 EB017183
6 · The paper itself

Abstract

Methods for joint activity reconstruction and attenuation reconstruction of time-of-flight (TOF) PET data provide an effective solution to attenuation correction when no (or incomplete or inaccurate) information on attenuation is available. One of the main barriers limiting use of these methods in clinical practice is their lack of validation in a relatively large patient database. In this contribution, we aim to validate reconstruction performed with maximum-likelihood activity reconstruction and attenuation registration (MLRR) in a whole-body patient dataset. Furthermore, a partial validation (because the scale problem of the algorithm is avoided for now) of reconstruction performed with maximum-likelihood activity and attenuation (MLAA) is also provided. We present a quantitative comparison between these 2 methods of joint reconstruction and the current clinical gold standard, maximum-likelihood expectation maximization (MLEM) with CT-based attenuation correction.

Indexed as

Positron-Emission TomographyAlgorithmsFluorodeoxyglucose F18HumansImage Processing, Computer-AssistedTime FactorsWhole Body ImagingFluorodeoxyglucose F18joint reconstructionquantitative analysistime-of-flight PET

Identifiers

PMID29496982
PMCPMC6167531

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.