Evidence map›Paper›PMID 29496960›Full record

SynthesisProceedings of the National Academy of Sciences of the United States of America2018

Modeling environmentally mediated rotavirus transmission: The role of temperature and hydrologic factors.

Alicia N M Kraay, Andrew F Brouwer, Nan Lin, Philip A Collender, Justin V Remais, Joseph N S Eisenberg

Open access · bronzeAbstract readMeta-Analysis
In one paragraph

Synthesis in Proceedings of the National Academy of Sciences of the United States of America, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed, 1 pooled it
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 1 synthesis or guideline pooled it, 55 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
  4. Article
  5. Waterborne diseases and climate change.Nature reviews. Microbiology · 2026
    Review
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  10. Review
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  14. Review
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  17. Uncovering social and environmental factors that increase the burden of climate-sensitive diarrheal infections on children.Proceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  18. Article
  19. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Alicia N M KraayDepartment of Epidemiology, University of Michigan, Ann Arbor, MI 48104.ORCID 0000-0002-7042-7048
Andrew F BrouwerDepartment of Environmental Health Sciences, University of California, Berkeley, CA 94720.
Nan LinDepartment of Environmental Health Sciences, University of California, Berkeley, CA 94720.
Philip A CollenderDepartment of Environmental Health Sciences, University of California, Berkeley, CA 94720.
Justin V RemaisDepartment of Environmental Health Sciences, University of California, Berkeley, CA 94720.
Joseph N S EisenbergDepartment of Epidemiology, University of Michigan, Ann Arbor, MI 48104; jnse@umich.edu.
University of Michigan · USUniversity of California, Berkeley · USBerkeley College · US

Funding

Environment Change and Diarrheal Disease: A Natural ExperimentR01AI050038 · NIAID · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI EISENBERG, JOSEPH N. S. · 2003 to 2012
$6.1M
Spatio-temporal data integration methods for infectious disease surveillanceR01AI125842 · NIAID · UNIVERSITY OF CALIFORNIA BERKELEY · PI CHANG, HOWARD H, REMAIS, JUSTIN V · 2017 to 2021
$3.6M
Modeling the Effects of the Environment on Enteric Pathogen DynamicsU01GM110712 · NIGMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI EISENBERG, JOSEPH N. S. · 2014 to 2018
$3.0M
Effects of agricultural expansion and intensification on infectionsR01TW010286 · FIC · UNIVERSITY OF SOUTH FLORIDA · PI REMAIS, JUSTIN V, ROHR, JASON ROBERT · 2015 to 2019
$2.4M
Models for improving surveillance of environmentally-mediated infectious diseasesK01AI091864 · NIAID · UNIVERSITY OF CALIFORNIA BERKELEY · PI REMAIS, JUSTIN V · 2011 to 2015
$643k
FIC NIH HHS R01 TW010286NIAID NIH HHS K01 AI091864NIAID NIH HHS R01 AI050038NIAID NIH HHS R01 AI125842NIGMS NIH HHS U01 GM110712
6 · The paper itself

Abstract

Rotavirus is considered a directly transmitted disease due to its high infectivity. Environmental pathways have, therefore, largely been ignored. Rotavirus, however, persists in water sources, and both its surface water concentrations and infection incidence vary with temperature. Here, we examine the potential for waterborne rotavirus transmission. We use a mechanistic model that incorporates both direct and waterborne transmission pathways, coupled with a hydrological model, and we simulate rotavirus transmission between two communities with interconnected water sources. To parameterize temperature dependency, we estimated temperature-dependent decay rates in water through a meta-analysis. Our meta-analysis suggests that rotavirus decay rates are positively associated with temperature (

Indexed as

Models, TheoreticalDisease OutbreaksEcuadorFresh WaterHumansHydrologyIncidenceRotavirusRotavirus InfectionsTemperatureTropical Climatepathogen persistencerotavirustemperaturetransmission modelingwaterborne

Identifiers

PMID29496960
PMCPMC5866583
OpenAlexW2793852982

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.