Evidence map›Paper›PMID 29496888›Full record

ArticleJournal of the American Society of Nephrology : JASN2018

Hemodialysis Induces an Acute Decline in Cerebral Blood Flow in Elderly Patients.

Harmke A Polinder-Bos, David Vállez García, Johanna Kuipers, Jan Willem J Elting, Marcel J H Aries, Wim P Krijnen, Henk Groen, Antoon T M Willemsen, Peter J van Laar, Fijanne Strijkert and 6 more

Erratum issuedAbstract read
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In one paragraph

Article in Journal of the American Society of Nephrology : JASN, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 111 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
111citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

111 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Cognitive Impairment in End Stage Renal Disease Patients Undergoing Hemodialysis: Markers and Risk Factors.International journal of environmental research and public health · 2022
    Pooled it
  2. Guideline
  3. Pooled it
  4. Dialysate Sodium Lowering in Maintenance Hemodialysis: A Randomized Clinical Trial.Clinical journal of the American Society of Nephrology : CJASN · 2024
    Trial
  5. Randomized trial comparing standard versus thermocontrolled haemodialysis using intradialytic cardiac, brain and renal magnetic resonance imaging.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2024
    Trial
  6. Kidney Disease, Hypertension Treatment, and Cerebral Perfusion and Structure.American journal of kidney diseases : the official journal of the National Kidney Foundation · 2022
    Trial
  7. Changes in cerebral oxygenation and cerebral blood flow during hemodialysis - A simultaneous near-infrared spectroscopy and positron emission tomography study.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2020
    Trial
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51 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

16 authors.

Harmke A Polinder-BosDivision of Nephrology, Department of Internal Medicine, H.A.Polinder-Bos@umcg.nl.
David Vállez GarcíaMedical Imaging Center, Department of Nuclear Medicine and Molecular Imaging, and.ORCID 0000-0003-3308-3167
Johanna KuipersDialysis Center Groningen, Groningen, The Netherlands.
Jan Willem J EltingDepartments of Neurology.
Marcel J H AriesDepartment of Intensive Care, Maastricht University Medical Center, Maastricht University, Maastricht, The Netherlands.
Wim P KrijnenResearch Group Healthy Ageing, Allied Health Care and Nursing, Hanze University of Applied Sciences, Groningen, The Netherlands.
Henk GroenEpidemiology.
Antoon T M WillemsenMedical Imaging Center, Department of Nuclear Medicine and Molecular Imaging, and.
Peter J van LaarRadiology, and.
Fijanne StrijkertNeuropsychology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.
Gert LuurtsemaMedical Imaging Center, Department of Nuclear Medicine and Molecular Imaging, and.
Riemer H J A SlartMedical Imaging Center, Department of Nuclear Medicine and Molecular Imaging, and.
Ralf WesterhuisDialysis Center Groningen, Groningen, The Netherlands.
Ron T GansevoortDivision of Nephrology, Department of Internal Medicine.
Carlo A J M GaillardDivision of Internal Medicine and Dermatology, Department of Nephrology, University Medical Center Utrecht, University of Utrecht, The Netherlands.
Casper F M FranssenDivision of Nephrology, Department of Internal Medicine.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The initiation of hemodialysis is associated with an accelerated decline of cognitive function and an increased incidence of cerebrovascular accidents and white matter lesions. Investigators have hypothesized that the repetitive circulatory stress of hemodialysis induces ischemic cerebral injury, but the mechanism is unclear. We studied the acute effect of conventional hemodialysis on cerebral blood flow (CBF), measured by [

Indexed as

Cerebrovascular CirculationAcute DiseaseAgedBrain IschemiaCognition DisordersFemaleHumansHypotensionKidney Failure, ChronicMagnetic Resonance ImagingMaleMental Status and Dementia TestsMiddle AgedNeuroimagingPositron Emission Tomography Computed TomographyRenal Dialysis[15O]H2O PETbrain perfusionchronic renal failureexecutive functiongeriatric nephrology

Identifiers

PMID29496888
PMCPMC5875962

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.