Evidence map›Paper›PMID 29496770›Full record

ArticleAmerican journal of critical care : an official publication, American Association of Critical-Care Nurses2018

Association Between Enteral Feeding, Weight Status, and Mortality in a Medical Intensive Care Unit.

Michael T Vest, Paul Kolm, James Bowen, Jillian Trabulsi, Shannon L Lennon, Mary Shapero, Patty McGraw, James Halbert, Claudine Jurkovitz

Abstract read
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Article in American journal of critical care : an official publication, American Association of Critical-Care Nurses, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

9 authors.

Michael T VestMichael T. Vest is an attending physician in the Pulmonary and Critical Care Section of the Department of Internal Medicine, a Value Institute Scholar at Christiana Care Value Institute, Newark, Delaware; and an assistant professor of medicine at the Sidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, Pennsylvania. Paul Kolm is director of biostatistics and James Bowen was a senior system engineer at Christiana Care Value Institute. Jillian Trabulsi is an associate professor, Department of Behavioral Health and Nutrition, and Shannon L. Lennon is an associate professor, Department of Kinesiology and Applied Physiology, University of Delaware, Newark, Delaware. Mary Shapero is a clinical nutrition manager in the Department of Nutrition, Patty McGraw is a research nurse supervisor in the Department of Internal Medicine Research, and James Halpert is the physical therapy program manager in the Department of Physical Therapy, Christiana Care Healthcare System, Newark, Delaware. Claudine Jurkovitz is a senior physician scientist at Christiana Care Value Institute. mvest@christianacare.org.
Paul KolmMichael T. Vest is an attending physician in the Pulmonary and Critical Care Section of the Department of Internal Medicine, a Value Institute Scholar at Christiana Care Value Institute, Newark, Delaware; and an assistant professor of medicine at the Sidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, Pennsylvania. Paul Kolm is director of biostatistics and James Bowen was a senior system engineer at Christiana Care Value Institute. Jillian Trabulsi is an associate professor, Department of Behavioral Health and Nutrition, and Shannon L. Lennon is an associate professor, Department of Kinesiology and Applied Physiology, University of Delaware, Newark, Delaware. Mary Shapero is a clinical nutrition manager in the Department of Nutrition, Patty McGraw is a research nurse supervisor in the Department of Internal Medicine Research, and James Halpert is the physical therapy program manager in the Department of Physical Therapy, Christiana Care Healthcare System, Newark, Delaware. Claudine Jurkovitz is a senior physician scientist at Christiana Care Value Institute.
James BowenMichael T. Vest is an attending physician in the Pulmonary and Critical Care Section of the Department of Internal Medicine, a Value Institute Scholar at Christiana Care Value Institute, Newark, Delaware; and an assistant professor of medicine at the Sidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, Pennsylvania. Paul Kolm is director of biostatistics and James Bowen was a senior system engineer at Christiana Care Value Institute. Jillian Trabulsi is an associate professor, Department of Behavioral Health and Nutrition, and Shannon L. Lennon is an associate professor, Department of Kinesiology and Applied Physiology, University of Delaware, Newark, Delaware. Mary Shapero is a clinical nutrition manager in the Department of Nutrition, Patty McGraw is a research nurse supervisor in the Department of Internal Medicine Research, and James Halpert is the physical therapy program manager in the Department of Physical Therapy, Christiana Care Healthcare System, Newark, Delaware. Claudine Jurkovitz is a senior physician scientist at Christiana Care Value Institute.
Jillian TrabulsiMichael T. Vest is an attending physician in the Pulmonary and Critical Care Section of the Department of Internal Medicine, a Value Institute Scholar at Christiana Care Value Institute, Newark, Delaware; and an assistant professor of medicine at the Sidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, Pennsylvania. Paul Kolm is director of biostatistics and James Bowen was a senior system engineer at Christiana Care Value Institute. Jillian Trabulsi is an associate professor, Department of Behavioral Health and Nutrition, and Shannon L. Lennon is an associate professor, Department of Kinesiology and Applied Physiology, University of Delaware, Newark, Delaware. Mary Shapero is a clinical nutrition manager in the Department of Nutrition, Patty McGraw is a research nurse supervisor in the Department of Internal Medicine Research, and James Halpert is the physical therapy program manager in the Department of Physical Therapy, Christiana Care Healthcare System, Newark, Delaware. Claudine Jurkovitz is a senior physician scientist at Christiana Care Value Institute.
Shannon L LennonMichael T. Vest is an attending physician in the Pulmonary and Critical Care Section of the Department of Internal Medicine, a Value Institute Scholar at Christiana Care Value Institute, Newark, Delaware; and an assistant professor of medicine at the Sidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, Pennsylvania. Paul Kolm is director of biostatistics and James Bowen was a senior system engineer at Christiana Care Value Institute. Jillian Trabulsi is an associate professor, Department of Behavioral Health and Nutrition, and Shannon L. Lennon is an associate professor, Department of Kinesiology and Applied Physiology, University of Delaware, Newark, Delaware. Mary Shapero is a clinical nutrition manager in the Department of Nutrition, Patty McGraw is a research nurse supervisor in the Department of Internal Medicine Research, and James Halpert is the physical therapy program manager in the Department of Physical Therapy, Christiana Care Healthcare System, Newark, Delaware. Claudine Jurkovitz is a senior physician scientist at Christiana Care Value Institute.
Mary ShaperoMichael T. Vest is an attending physician in the Pulmonary and Critical Care Section of the Department of Internal Medicine, a Value Institute Scholar at Christiana Care Value Institute, Newark, Delaware; and an assistant professor of medicine at the Sidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, Pennsylvania. Paul Kolm is director of biostatistics and James Bowen was a senior system engineer at Christiana Care Value Institute. Jillian Trabulsi is an associate professor, Department of Behavioral Health and Nutrition, and Shannon L. Lennon is an associate professor, Department of Kinesiology and Applied Physiology, University of Delaware, Newark, Delaware. Mary Shapero is a clinical nutrition manager in the Department of Nutrition, Patty McGraw is a research nurse supervisor in the Department of Internal Medicine Research, and James Halpert is the physical therapy program manager in the Department of Physical Therapy, Christiana Care Healthcare System, Newark, Delaware. Claudine Jurkovitz is a senior physician scientist at Christiana Care Value Institute.
Patty McGrawMichael T. Vest is an attending physician in the Pulmonary and Critical Care Section of the Department of Internal Medicine, a Value Institute Scholar at Christiana Care Value Institute, Newark, Delaware; and an assistant professor of medicine at the Sidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, Pennsylvania. Paul Kolm is director of biostatistics and James Bowen was a senior system engineer at Christiana Care Value Institute. Jillian Trabulsi is an associate professor, Department of Behavioral Health and Nutrition, and Shannon L. Lennon is an associate professor, Department of Kinesiology and Applied Physiology, University of Delaware, Newark, Delaware. Mary Shapero is a clinical nutrition manager in the Department of Nutrition, Patty McGraw is a research nurse supervisor in the Department of Internal Medicine Research, and James Halpert is the physical therapy program manager in the Department of Physical Therapy, Christiana Care Healthcare System, Newark, Delaware. Claudine Jurkovitz is a senior physician scientist at Christiana Care Value Institute.
James HalbertMichael T. Vest is an attending physician in the Pulmonary and Critical Care Section of the Department of Internal Medicine, a Value Institute Scholar at Christiana Care Value Institute, Newark, Delaware; and an assistant professor of medicine at the Sidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, Pennsylvania. Paul Kolm is director of biostatistics and James Bowen was a senior system engineer at Christiana Care Value Institute. Jillian Trabulsi is an associate professor, Department of Behavioral Health and Nutrition, and Shannon L. Lennon is an associate professor, Department of Kinesiology and Applied Physiology, University of Delaware, Newark, Delaware. Mary Shapero is a clinical nutrition manager in the Department of Nutrition, Patty McGraw is a research nurse supervisor in the Department of Internal Medicine Research, and James Halpert is the physical therapy program manager in the Department of Physical Therapy, Christiana Care Healthcare System, Newark, Delaware. Claudine Jurkovitz is a senior physician scientist at Christiana Care Value Institute.
Claudine JurkovitzMichael T. Vest is an attending physician in the Pulmonary and Critical Care Section of the Department of Internal Medicine, a Value Institute Scholar at Christiana Care Value Institute, Newark, Delaware; and an assistant professor of medicine at the Sidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, Pennsylvania. Paul Kolm is director of biostatistics and James Bowen was a senior system engineer at Christiana Care Value Institute. Jillian Trabulsi is an associate professor, Department of Behavioral Health and Nutrition, and Shannon L. Lennon is an associate professor, Department of Kinesiology and Applied Physiology, University of Delaware, Newark, Delaware. Mary Shapero is a clinical nutrition manager in the Department of Nutrition, Patty McGraw is a research nurse supervisor in the Department of Internal Medicine Research, and James Halpert is the physical therapy program manager in the Department of Physical Therapy, Christiana Care Healthcare System, Newark, Delaware. Claudine Jurkovitz is a senior physician scientist at Christiana Care Value Institute.

Funding

Predictive Modeling & Optimal Control Framework for Model-Based Epidemic Response in DelawareP20GM103446 · NIGMS · UNIVERSITY OF DELAWARE · PI Anjana Narayan Bhat · 2012 to 2026
$67.2M
Subproject Title: Clinical Research Education, Mentoring and Career Development CoreU54GM104941 · NIGMS · UNIVERSITY OF DELAWARE · PI Gregory E Hicks · 2013 to 2026
$60.5M
NIGMS NIH HHS P20 GM103446NIGMS NIH HHS U54 GM104941
6 · The paper itself

Abstract

backgroundClinical practice guidelines recommend enteral nutrition for most patients receiving mechanical ventilation. However, recently published evidence on the effect of enteral nutrition on mortality, particularly for patients who are well nourished, is conflicting.

objectivesTo examine the association between enteral feeding and hospital mortality in critically ill patients receiving mechanical ventilation and to determine if body mass index mediates this relationship.

methodsA retrospective cohort study of patients receiving mechanical ventilation admitted to a medical intensive care unit in 2013. Demographic and clinical variables were collected. Cox proportional hazards regression was used to examine the relationship between an enteral feeding order and hospital mortality and to determine if the relationship was mediated by body mass index.

resultsOf 777 patients who had 811 hospitalizations requiring mechanical ventilation, 182 (23.4%) died in the hospital. A total of 478 patients (61.5%) received an order for enteral tube feeding, which was associated with a lower risk of death (hazard ratio, 0.41; 95% CI, 0.29-0.59). Body mass index did not mediate the relationship between mortality and receipt of an order for enteral feeding. Median stay in the unit was 3.6 days. Most deaths (72.0%) occurred more than 48 hours after admission.

conclusionThe finding of a positive association between an order for enteral feeding and survival supports enteral feeding of patients in medical intensive care units. Furthermore, the beneficial effect of enteral feeding appears to apply to patients regardless of body mass index.

Indexed as

AdultAgedBody WeightCritical CareCritical IllnessEnteral NutritionFemaleHospital MortalityHumansIntensive Care UnitsMaleMiddle AgedRespiration, ArtificialRetrospective Studies

Identifiers

PMID29496770
PMCPMC6519919

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.