ArticleThe journal of pain2018
Within-Person Pain Variability and Mental Health in Older Adults With Osteoarthritis: An Analysis Across 6 European Cohorts.
Article in The journal of pain, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 2 of them syntheses that pooled it.
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The trial behind it
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Who cites it
18 citing papers in PubMed, 2 syntheses or guidelines pooled it, 36 citations in OpenAlex.
- The association between psychosocial factors and mental health symptoms in cervical spine pain with or without radiculopathy on health outcomes: a systematic review.BMC musculoskeletal disorders · 2023Pooled it
- Pooled it
- Osteoarthritis and Degree of Fatigue are Associated with Pain Levels in Patients with Fibromyalgia Syndrome: A Cross-Sectional Study of 394 Patients.International journal of general medicine · 2025Trial
- Managing Osteoarthritis Pain in Underrepresented Populations: Insights from Mexico and Latin America.Journal of clinical medicine · 2026Review
- The association of intensity of joint pain and health-related quality of life among adults with arthritis: a large population-based cross-sectional study.Arthritis research & therapy · 2025Article
- A population-based survey of beliefs about neck pain and its associated disorders: a cross-sectional study.BMC musculoskeletal disorders · 2025Article
- Impact of intraindividual pain variability on functional pain outcomes among adults with chronic pain: an ecological momentary assessment study.Journal of behavioral medicine · 2025Article
- Associations Between Daily Symptoms and Pain Flares in Rheumatoid Arthritis: Case-Crossover mHealth Study.JMIR mHealth and uHealth · 2025Article
- Short-term Frailty Index Fluctuations in Older Adults: Noise or Signal?The journals of gerontology. Series A, Biological sciences and medical sciences · 2024Article
- Anxiety and depression prevalence and associated factors in patients with knee osteoarthritis.Frontiers in psychiatry · 2024Article
- Time to evolve: the applicability of pain phenotyping in manual therapy.The Journal of manual & manipulative therapy · 2022Article
- Temporomandibular disorders cases with high-impact pain are more likely to experience short-term pain fluctuations.Scientific reports · 2022Article
- How Are Neighborhood Characteristics Associated With Mental and Physical Functioning Among Older Adults With Radiographic Knee Osteoarthritis?Arthritis care & research · 2021Article
- Depression negatively affects patient-reported knee functional outcome after intraarticular hyaluronic acid injection among geriatric patients with knee osteoarthritis.Journal of orthopaedic surgery and research · 2019Article
- Within-person pain variability and physical activity in older adults with osteoarthritis from six European countries.BMC musculoskeletal disorders · 2019Article
- Neuropathic Pain Prevalence of Older Adults in an Urban Area of Iran: A Population-Based Study.Pain research and treatment · 2019Article
- Worsen depression after viscosupplementation treatment for geriatric people with knee osteoarthritis?International journal of clinical and health psychology : IJCHP · 2019Article
- Article
Corrections and comments
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Authors and funding
18 authors at 10 institutions in 6 countries.
Funding
Abstract
Pain is a key symptom of osteoarthritis (OA) and has been linked to poor mental health. Pain fluctuates over time within individuals, but a paucity of studies have considered day-to-day fluctuations of joint pain in relation to affective symptoms in older persons with OA. This study investigated the relationship of pain severity as well as within-person pain variability with anxiety and depression symptoms in 832 older adults with OA who participated in the European Project on OSteoArthritis (EPOSA): a 6-country cohort study. Affective symptoms were examined with the Hospital Anxiety and Depression Scale, pain severity was assessed with the Western Ontario and McMaster Universities OA Index and the Australian/Canadian Hand Osteoarthritis Index, and intraindividual pain variability was measured using pain calendars assessed at baseline, 6, and 12 to 18 months. Age-stratified multiple linear regression analyses adjusted for relevant confounders showed that more pain was associated with more affective symptoms in older-old participants (74.1-85 years). Moreover, older-old participants experienced fewer symptoms of anxiety (ratio = .85, 95% confidence interval [CI], .77-.94), depression (ratio = .90, 95% CI, .82-.98), and total affective symptoms (ratio = .87, 95% CI, .79-.94) if their pain fluctuated more. No such association was evident in younger-old participants (65-74.0 years). These findings imply that stable pain levels are more detrimental to mental health than fluctuating pain levels in older persons. PERSPECTIVE: This study showed that more severe and stable joint pain levels were associated with anxiety and depressive symptoms in older persons with OA. These findings emphasize the importance of measuring pain in OA at multiple time points, because joint pain fluctuations may be an indicator for the presence of affective symptoms.
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Registered trials
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