Evidence map›Paper›PMID 29495948›Full record

ArticleGlobal health action2018

Harmful alcohol drinking among HIV-positive people in Nepal: an overlooked threat to anti-retroviral therapy adherence and health-related quality of life.

Khem Narayan Pokhrel, Kalpana Gaulee Pokhrel, Sanjeev Raj Neupane, Vidya Dev Sharma

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Global health action, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04054466 (Effectiveness of the Nursing Counseling to the Change of Behavior of Alcohol Consumption in Patients Receiving HAART), which is not on this map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
1.3field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04054466 nacompletednot on this map

Effectiveness of the Nursing Counseling to the Change of Behavior of Alcohol Consumption in Patients Receiving HAART

TypeinterventionalSponsorUniversidad Peruana Cayetano HerediaRan2018 to 2020Enrolled233ConditionsHIV, Alcohol DrinkingArmsNursing Counseling in the change of Alcohol Consumption Behavior in patients receiving HAART, Habitual Counseling
3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it, 23 citations in OpenAlex.

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  8. Health-related quality of life in reproductive-age women on antiretroviral therapy: a cross sectional study in Ethiopia.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Khem Narayan Pokhrela Department of HIV, Nutrition, and Health , Health Research and Social Development Forum , Kathmandu , Nepal.
Kalpana Gaulee Pokhrelb Department of HIV and Nutrition , Integrated Development Foundation , Kathmandu , Nepal.
Sanjeev Raj Neupaneb Department of HIV and Nutrition , Integrated Development Foundation , Kathmandu , Nepal.
Vidya Dev Sharmac Department of Psychiatry and Mental Health, Institute of Medicine , Tribhuwan University , Kathmandu , Nepal.
Nepal Health Research Council · NPTribhuvan University · NP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPeople living with Human Immunodeficiency Virus (HIV) often suffer from alcohol-use disorders resulting in their poor health and treatment outcomes. Little is known about the association of harmful alcohol drinking with their adherence to anti-retroviral therapy (ART) and health-related quality of life (QOL) in low-resource settings.

objectiveThis study aimed to investigate associations between harmful alcohol drinking, adherence to ART and health-related QOL in HIV-positive people, stratified by gender, in Nepal.

methodsWe conducted a cross-sectional study of 682 HIV-positive people on ART to measure their self-reported harmful alcohol drinking and non-adherence to ART in the previous month of data collection. We also measured health-related QOL using a WHOQOL-HIV BREF scale. The association between harmful alcohol drinking and non-adherence to ART was examined using multiple logistic regressions. Additionally, multiple linear regressions examined association between harmful alcohol drinking and QOL.

resultsHarmful alcohol drinking was associated with non-adherence to ART among men (AOR: 2.48, 95% CI: 1.50, 4.11, p < 0.001) and women (AOR: 2.52, 95% CI: 1.32, 4.80, p = 0.005). Men were more likely to have lower score for the psychological (β = -0.55, p = 0.021) and level of independence (β = -0.68, p = 0.018) domains when they had harmful alcohol drinking. Moreover, women were more likely to have lower scores for the physical (β = -1.01, p = 0.015), social relations (β = -0.82, p = 0.033), environmental (β = -0.88, p = 0.011), and spiritual (β = -1.30, p = 0.005) domains of QOL when they had harmful alcohol drinking.

conclusionsHarmful alcohol drinking had a negative association with ART adherence and QOL in both HIV-positive men and women in Nepal. Screening for alcohol-use disorders and community-based counseling services should be provided while delivering ART services to improve treatment adherence and QOL.

Indexed as

Drug MonitoringQuality of LifeAdultAlcoholismAnti-Retroviral AgentsCross-Sectional StudiesEnvironmentFemaleHIV InfectionsHIV SeropositivityHumansInterpersonal RelationsMaleNepalSelf ReportSex FactorsAnti-Retroviral Agentsanti-retroviral therapyharmful alcohol drinkingHIVNepalquality of life

Identifiers

PMID29495948
PMCPMC5844022
OpenAlexW2790054537

What OpenQuestion holds

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LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.