Evidence map›Paper›PMID 29495598›Full record

ReviewInternational journal of molecular sciences2018

Potential Health Benefits of Olive Oil and Plant Polyphenols.

Monika Gorzynik-Debicka, Paulina Przychodzen, Francesco Cappello, Alicja Kuban-Jankowska, Antonella Marino Gammazza, Narcyz Knap, Michal Wozniak, Magdalena Gorska-Ponikowska

Registry-linked trialOpen access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05040620 (Effectiveness of Olive Oil Local Application in Decreasing the Period of Alignment Phase in Non Extraction Orthodontic Patients. A Randomized Controlled Clinical Trial.), which is not on this map. Cited by 268 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
268citing papers in PubMed, 7 pooled it
28.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05040620 phase1unknown statusnot on this mapstarted 2020, after this paper: background citation

Effectiveness of Olive Oil Local Application in Decreasing the Period of Alignment Phase in Non Extraction Orthodontic Patients. A Randomized Controlled Clinical Trial.

TypeinterventionalSponsorMinia UniversityRan2020 to 2022Enrolled110ConditionsOrthodontic Tooth MovementArmsOlive Oil Topical Oil
3 · Its place in the literature

Who cites it

268 citing papers in PubMed, 7 syntheses or guidelines pooled it, 631 citations in OpenAlex.

  1. Pooled it
  2. Enzyme Inhibition by Bioactive Compounds from Olive (Molecules (Basel, Switzerland) · 2026
    Pooled it
  3. Pooled it
  4. Pooled it
  5. Pooled it
  6. Pooled it
  7. Pooled it
  8. Trial
  9. Trial
  10. Effects of High-Phenolic Extra Virgin Olive Oil on Sensory Processing in Children With Autism Spectrum Disorder: A Pilot Study.International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience · 2026
    Article
  11. Review
  12. Review
  13. Article
  14. Article
  15. Bioactive Fractions fromMolecules (Basel, Switzerland) · 2026
    Article
  16. Review
  17. Article
  18. Review
  19. MAFLD: a ferroptotic disease.Trends in molecular medicine · 2026
    Review
  20. Article

208 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 3 countries.

Monika Gorzynik-DebickaDepartment of Medical Chemistry, Medical University of Gdansk, 80-211 Gdańsk, Poland. gorzynikdebicka@gmail.com.
Paulina PrzychodzenDepartment of Medical Chemistry, Medical University of Gdansk, 80-211 Gdańsk, Poland. p.e.przychodzen@gumed.edu.pl.
Francesco CappelloDepartment of Experimental Biomedicine and Clinical Neurosciences (BioNeC), University of Palermo, 90127 Palermo, Italy. francapp@hotmail.com.
Alicja Kuban-JankowskaDepartment of Medical Chemistry, Medical University of Gdansk, 80-211 Gdańsk, Poland. alicjakuban@gumed.edu.pl.
Antonella Marino GammazzaDepartment of Experimental Biomedicine and Clinical Neurosciences (BioNeC), University of Palermo, 90127 Palermo, Italy. antonella.marino@hotmail.it.
Narcyz KnapDepartment of Medical Chemistry, Medical University of Gdansk, 80-211 Gdańsk, Poland. narcyz@gumed.edu.pl.
Michal WozniakDepartment of Medical Chemistry, Medical University of Gdansk, 80-211 Gdańsk, Poland. mwozniak@gumed.edu.pl.
Magdalena Gorska-PonikowskaDepartment of Medical Chemistry, Medical University of Gdansk, 80-211 Gdańsk, Poland. m.gorska@gumed.edu.pl.
Gdańsk Medical University · PLUniversity of Palermo · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Beneficial effects of natural plant polyphenols on the human body have been evaluated in a number of scientific research projects. Bioactive polyphenols are natural compounds of various chemical structures. Their sources are mostly fruits, vegetables, nuts and seeds, roots, bark, leaves of different plants, herbs, whole grain products, processed foods (dark chocolate), as well as tea, coffee, and red wine. Polyphenols are believed to reduce morbidity and/or slow down the development of cardiovascular and neurodegenerative diseases as well as cancer. Biological activity of polyphenols is strongly related to their antioxidant properties. They tend to reduce the pool of reactive oxygen species as well as to neutralize potentially carcinogenic metabolites. A broad spectrum of health-promoting properties of plant polyphenols comprises antioxidant, anti-inflammatory, anti-allergic, anti-atherogenic, anti-thrombotic, and anti-mutagenic effects. Scientific studies present the ability of polyphenols to modulate the human immune system by affecting the proliferation of white blood cells, and also the production of cytokines or other factors that participate in the immunological defense. The aim of the review is to focus on polyphenols of olive oil in context of their biological activities.

Indexed as

AnimalsAntineoplastic Agents, PhytogenicAntioxidantsHumansOleaOlive OilPhytochemicalsPlant ExtractsPlant LeavesPolyphenolsAntineoplastic Agents, PhytogenicAntioxidantsOlive OilPhytochemicalsPlant ExtractsPolyphenolsanticancer therapyhydroxytyrosolOlea europeaoleuropeinolive oilpolyphenols

Identifiers

PMID29495598
PMCPMC5877547
OpenAlexW2794365389

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.