Evidence map›Paper›PMID 29495578›Full record

ArticleNutrients2018

Cucumis sativus Aqueous Fraction Inhibits Angiotensin II-Induced Inflammation and Oxidative Stress In Vitro.

Celeste Trejo-Moreno, Marisol Méndez-Martínez, Alejandro Zamilpa, Enrique Jiménez-Ferrer, Maria Dolores Perez-Garcia, Omar N Medina-Campos, José Pedraza-Chaverri, María Angélica Santana, Fernando R Esquivel-Guadarrama, Aida Castillo and 3 more

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.0field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 23 citations in OpenAlex.

  1. GenusChinese herbal medicines · 2026
    Review
  2. Cucumber (Journal of pharmacopuncture · 2023
    Article
  3. Aqueous Fraction fromNutrients · 2023
    Article
  4. Metabolite profiling, hypolipidemic, and anti-atherosclerosis activity of mixed vegetable fermentation extract.Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society · 2023
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 4 institutions in 1 country.

Celeste Trejo-MorenoInstituto de Investigación en Ciencias Básicas y Aplicadas, Universidad Autónoma del Estado de Morelos, Av. Universidad 1001, Cuernavaca, Morelos CP 62209, Mexico. trejomc@hotmail.com.
Marisol Méndez-MartínezInstituto de Investigación en Ciencias Básicas y Aplicadas, Universidad Autónoma del Estado de Morelos, Av. Universidad 1001, Cuernavaca, Morelos CP 62209, Mexico. mm.mary87@gmail.com.
Alejandro ZamilpaLaboratorio de Farmacología, Centro de Investigación Biomédica del Sur, Instituto Mexicano del Seguro Social, Republica de Argentina 1, Xochitepec, Morelos CP 62790, Mexico. azamilpa_2000@yahoo.com.mx.ORCID 0000-0002-2233-5958
Enrique Jiménez-FerrerLaboratorio de Farmacología, Centro de Investigación Biomédica del Sur, Instituto Mexicano del Seguro Social, Republica de Argentina 1, Xochitepec, Morelos CP 62790, Mexico. enriqueferrer_mx@yahoo.com.ORCID 0000-0002-0783-8274
Maria Dolores Perez-GarciaLaboratorio de Farmacología, Centro de Investigación Biomédica del Sur, Instituto Mexicano del Seguro Social, Republica de Argentina 1, Xochitepec, Morelos CP 62790, Mexico. lola_as@yahoo.com.mx.
Omar N Medina-CamposDepartamento de Biología, Facultad de Química, Universidad Nacional Autónoma de México, Coyoacán, Mexico City CP 04510, Mexico. omarnoelmedina@gmail.com.
José Pedraza-ChaverriDepartamento de Biología, Facultad de Química, Universidad Nacional Autónoma de México, Coyoacán, Mexico City CP 04510, Mexico. pedrazachaverri@gmail.com.
María Angélica SantanaCentro de Investigación en Dinámica Celular (IICBA), Universidad Autónoma del Estado de Morelos, Av. Universidad 1001, Cuernavaca, Morelos CP 62209, Mexico. santana@uaem.mx.
Fernando R Esquivel-GuadarramaFacultad de Medicina, Universidad Autónoma del Estado de Morelos, Leñeros S/N, Cuernavaca, Morelos CP 62350, Mexico. fernando.esquivel@uaem.mx.
Aida CastilloDepartamento de Fisiología Biofísica y Neurociencias del Centro de Investigación y Estudios Avanzados del Instituto Politécnico Nacional (CINVESTAV del IPN), Mexico City CP 07360, Mexico. aidacast10@hotmail.com.
Jacquelynne Cervantes-TorresDepartamento de Inmunología, Instituto de Investigaciones Biomédicas, Universidad Nacional Autónoma de México, Coyoacán, Mexico City CP 04510, Mexico. jcervantes@iibiomedicas.unam.mx.
Gladis FragosoDepartamento de Inmunología, Instituto de Investigaciones Biomédicas, Universidad Nacional Autónoma de México, Coyoacán, Mexico City CP 04510, Mexico. gladis@unam.mx.
Gabriela Rosas-SalgadoFacultad de Medicina, Universidad Autónoma del Estado de Morelos, Leñeros S/N, Cuernavaca, Morelos CP 62350, Mexico. gabriela.rosas@uaem.mx.
Universidad Autónoma del Estado de Morelos · MXUniversidad Nacional Autónoma de México · MXMexican Social Security Institute · MXCentro de Investigación y de Estudios Avanzados del Instituto Politécnico Nacional · MX

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Inflammation and oxidative stress play major roles in endothelial dysfunction, and are key factors in the progression of cardiovascular diseases. The aim of this study was to evaluate in vitro the effect of three subfractions (SFs) from the

Indexed as

Cucumis sativusAmino AcidsAngiotensin IIAnti-Inflammatory AgentsAntioxidantsCell Adhesion MoleculesCell LineDose-Response Relationship, DrugEndothelial CellsHumansInflammationInflammation MediatorsInterleukin-6Nitric OxideOxidative StressPhytotherapyAmino AcidsAngiotensin IIAnti-Inflammatory AgentsAntioxidantsCell Adhesion MoleculesIL6 protein, humanInflammation MediatorsInterleukin-6Nitric OxidePlant ExtractsReactive Oxygen Speciesangiotensin IICucumis sativusinflammationROS

Identifiers

PMID29495578
PMCPMC5872694
OpenAlexW2790362858

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.