Evidence map›Paper›PMID 29495550›Full record

ArticleMolecules (Basel, Switzerland)2018

Exploring N-acyl-4-azatetracyclo[5.3.2.0

Rosana Leiva, Andrew McBride, Margaret Binnie, Scott P Webster, Santiago Vázquez

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecules (Basel, Switzerland), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Rosana LeivaLaboratori de Química Farmacèutica (Unitat Associada al CSIC), Facultat de Farmàcia i Ciències de l'Alimentació, and Institute of Biomedicine (IBUB), Universitat de Barcelona, Av. Joan XXIII, 27-31, E-08028 Barcelona, Spain. rosana.leiva58@gmail.com.
Andrew McBrideCentre for Cardiovascular Science, University of Edinburgh, Queen's Medical Research Institute, Edinburgh EH16 4TJ, UK. a.mcbride@ed.ac.uk.
Margaret BinnieCentre for Cardiovascular Science, University of Edinburgh, Queen's Medical Research Institute, Edinburgh EH16 4TJ, UK. mbinnie@ed.ac.uk.
Scott P WebsterCentre for Cardiovascular Science, University of Edinburgh, Queen's Medical Research Institute, Edinburgh EH16 4TJ, UK. scott.webster@ed.ac.uk.
Santiago VázquezLaboratori de Química Farmacèutica (Unitat Associada al CSIC), Facultat de Farmàcia i Ciències de l'Alimentació, and Institute of Biomedicine (IBUB), Universitat de Barcelona, Av. Joan XXIII, 27-31, E-08028 Barcelona, Spain. svazquez@ub.edu.ORCID 0000-0002-9296-6026

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We recently found that a cyclohexanecarboxamide derived from 4-azatetracyclo[5.3.2.0

Indexed as

11-beta-Hydroxysteroid Dehydrogenase Type 1Chemistry Techniques, SyntheticDrug DesignEnzyme ActivationEnzyme InhibitorsHumansInhibitory Concentration 50Magnetic Resonance SpectroscopyStructure-Activity Relationship11-beta-Hydroxysteroid Dehydrogenase Type 1Enzyme Inhibitors11β-HSD1drug discoveryenzyme inhibitorspolycyclic hydrocarbonsSAR investigation

Identifiers

PMID29495550
PMCPMC6017749

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.