Evidence map›Paper›PMID 29495530›Full record

ArticleInternational journal of environmental research and public health2018

Sodium Dodecyl Sulphate-Supported Nanocomposite as Drug Carrier System for Controlled Delivery of Ondansetron.

Gaurav Sharma, Mu Naushad, Bharti Thakur, Amit Kumar, Poonam Negi, Reena Saini, Anterpreet Chahal, Ashok Kumar, Florian J Stadler, U M H Aqil

Abstract read
In one paragraph

Article in International journal of environmental research and public health, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Gaurav SharmaShenzhen Key Laboratory of Polymer Science and Technology, Guangdong Research Center for Interfacial Engineering of Functional Materials, Nanshan District Key Lab for Biopolymers and Safety Evaluation, College of Materials Science and Engineering, Shenzhen University, Shenzhen 518060, China. gaurav8777@gmail.com.
Mu NaushadDepartment of Chemistry, College of Science, Bld.#5, King Saud University, Riyadh 11451, Saudi Arabia. mnaushad@ksu.edu.sa.ORCID 0000-0001-6056-587X
Bharti ThakurSchool of Chemistry, Shoolini University, Solan 173212, India. bt3456thakur@gmail.com.
Amit KumarShenzhen Key Laboratory of Polymer Science and Technology, Guangdong Research Center for Interfacial Engineering of Functional Materials, Nanshan District Key Lab for Biopolymers and Safety Evaluation, College of Materials Science and Engineering, Shenzhen University, Shenzhen 518060, China. mittuchem83@gmail.com.
Poonam NegiSchool of Pharmaceutical Sciences, Shoolini University, Solan 173212, India. poonamgarge@gmail.com.ORCID 0000-0003-3722-991X
Reena SainiSchool of Applied Science and Biotechnology, Shoolini University, Solan 173212, India. reenavohra10@gmail.com.
Anterpreet ChahalSchool of Applied Science and Biotechnology, Shoolini University, Solan 173212, India. chahal2407@gmail.com.
Ashok KumarDepartment of Biotechnology and Bioinformatics, Jaypee University of Information Technology, Waknaghat, Solan 173234, India. ashok.nadda09@gmail.com.
Florian J StadlerShenzhen Key Laboratory of Polymer Science and Technology, Guangdong Research Center for Interfacial Engineering of Functional Materials, Nanshan District Key Lab for Biopolymers and Safety Evaluation, College of Materials Science and Engineering, Shenzhen University, Shenzhen 518060, China. fjstadler@szu.edu.cn.ORCID 0000-0002-5849-1485
U M H AqilSchool of Public Health, 3rd Floor, SRM Medical College and Research, Centre, Kattankulathur 603211, India. haideraqil@gmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Sodium dodecyl sulphate-supported iron silicophosphate (SDS/FeSP) nanocomposite was successfully fabricated by the co-precipitation method. The SDS/FeSP nanocomposite was investigated as a drug carrier for ondansetron. The cumulative drug release of ondansetron was observed at various pH values for different time intervals, i.e., from 20 min to 48 h. A ranking of the drug release was observed at different pHs; pH 2.2 > saline (pH 5.5) > pH 7.4 > pH 9.4 > distilled water. Maximum release of encapsulated drug was found to be about 45.38% at pH 2.2. The cell viability tests of SDS/FeSP nanocomposite concluded that SDS/FeSP nanocomposite was non-cytotoxic in nature.

Indexed as

Drug CarriersNanocompositesSodium Dodecyl SulfateAntiemeticsCell SurvivalHumansOndansetronToxicity TestsAntiemeticsDrug CarriersOndansetronSodium Dodecyl Sulfatedrug deliverynanocompositeondansetronsodium dodecyl sulphate

Identifiers

PMID29495530
PMCPMC5876959

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.