Evidence map›Paper›PMID 29495512›Full record

ArticleGenes2018

Characterizing the DNA Methyltransferases of Haloferax volcanii via Bioinformatics, Gene Deletion, and SMRT Sequencing.

Matthew Ouellette, J Peter Gogarten, Jessica Lajoie, Andrea M Makkay, R Thane Papke

Open access · goldAbstract read
In one paragraph

Article in Genes, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
2.9field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 23 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Article
  6. The extremophileFrontiers in microbiology · 2023
    Article
  7. DNA Methyltransferases: From Evolution to Clinical Applications.International journal of molecular sciences · 2022
    Review
  8. Article
  9. Article
  10. Article
  11. Open biology · 2020
    Review
  12. Article
  13. Article
  14. Article
  15. The Role of Archaeal Chromatin in Transcription.Journal of molecular biology · 2019
    Review
  16. Methylomes of Two Extremely HalophilicMicrobiology resource announcements · 2019
    Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Matthew OuelletteDepartment of Molecular and Cell Biology, University of Connecticut, Storrs, CT 06268, USA. matthew.ouellette@uconn.edu.
J Peter GogartenDepartment of Molecular and Cell Biology, University of Connecticut, Storrs, CT 06268, USA. gogarten@uconn.edu.ORCID 0000-0001-6459-6518
Jessica LajoieDepartment of Molecular and Cell Biology, University of Connecticut, Storrs, CT 06268, USA. jessica.lajoie@uconn.edu.
Andrea M MakkayDepartment of Molecular and Cell Biology, University of Connecticut, Storrs, CT 06268, USA. andrea.makkay@uconn.edu.
R Thane PapkeDepartment of Molecular and Cell Biology, University of Connecticut, Storrs, CT 06268, USA. thane@uconn.edu.
University of Connecticut · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

DNA methyltransferases (MTases), which catalyze the methylation of adenine and cytosine bases in DNA, can occur in bacteria and archaea alongside cognate restriction endonucleases (REases) in restriction-modification (RM) systems or independently as orphan MTases. Although DNA methylation and MTases have been well-characterized in bacteria, research into archaeal MTases has been limited. A previous study examined the genomic DNA methylation patterns (methylome) of the halophilic archaeon

Indexed as

CTAG methylationDNA methylationGATC methylationhaloarchaeaHalobacteriaHaloferax volcaniimethylationmethylomerestriction-modification system

Identifiers

PMID29495512
PMCPMC5867850
OpenAlexW2792215411

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.