Evidence map›Paper›PMID 29495412›Full record

ArticleMolecules (Basel, Switzerland)2018

Design of Two Alternative Routes for the Synthesis of Naftifine and Analogues as Potential Antifungal Agents.

Rodrigo Abonia, Alexander Garay, Juan C Castillo, Braulio Insuasty, Jairo Quiroga, Manuel Nogueras, Justo Cobo, Estefanía Butassi, Susana Zacchino

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.0field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 17 citations in OpenAlex.

  1. Review
  2. Synthesis and Biological Studies of Benzo[Pharmaceuticals (Basel, Switzerland) · 2023
    Review
  3. Review
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 3 countries.

Rodrigo AboniaGrupo de Investigación de Compuestos Heterocíclicos (GICH), Departamento de Química, Universidad del Valle, A. A. 25360 Cali, Colombia. rodrigo.abonia@correounivalle.edu.co.
Alexander GarayGrupo de Investigación de Compuestos Heterocíclicos (GICH), Departamento de Química, Universidad del Valle, A. A. 25360 Cali, Colombia. talero22@hotmail.co.
Juan C CastilloGrupo de Investigación de Compuestos Heterocíclicos (GICH), Departamento de Química, Universidad del Valle, A. A. 25360 Cali, Colombia. juan.castillo06@uptc.edu.co.ORCID 0000-0002-6060-2578
Braulio InsuastyGrupo de Investigación de Compuestos Heterocíclicos (GICH), Departamento de Química, Universidad del Valle, A. A. 25360 Cali, Colombia. braulio.insuasty@correounivalle.edu.co.
Jairo QuirogaGrupo de Investigación de Compuestos Heterocíclicos (GICH), Departamento de Química, Universidad del Valle, A. A. 25360 Cali, Colombia. jairo.quiroga@correounivalle.edu.co.ORCID 0000-0002-9451-3063
Manuel NoguerasDepartment of Inorganic and Organic Chemistry, Universidad de Jaén, 23071 Jaén, Spain. mmontiel@ujaen.es.ORCID 0000-0001-5976-0387
Justo CoboDepartment of Inorganic and Organic Chemistry, Universidad de Jaén, 23071 Jaén, Spain. jcobo@ujaen.es.ORCID 0000-0001-9184-2390
Estefanía ButassiÁrea de Farmacognosia, Facultad de Ciencias Bioquímicas y Farmacéuticas, Universidad Nacional de Rosario, Suipacha 531, CP 2000 Rosario, Argentina. fefabutassi@hotmail.com.
Susana ZacchinoÁrea de Farmacognosia, Facultad de Ciencias Bioquímicas y Farmacéuticas, Universidad Nacional de Rosario, Suipacha 531, CP 2000 Rosario, Argentina. szaabgil@citynet.net.ar.ORCID 0000-0002-7112-5500
Universidad del Valle · CONational University of Rosario · ARUniversidad de Jaén · ESPedagogical and Technological University of Colombia · CO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Two practical and efficient approaches have been implemented as alternative procedures for the synthesis of naftifine and novel diversely substituted analogues

Indexed as

Chemistry Techniques, SyntheticDrug DesignAllylamineAntifungal AgentsCatalysisDose-Response Relationship, DrugFungiMicrobial Sensitivity TestsMolecular StructureAllylamineAntifungal Agentsnaftifineallyaminesantifungal activitybenzylaminesMannich-type reactionnaftifine analoguespropiophenone saltsγ-aminoalcohols

Identifiers

PMID29495412
PMCPMC6017661
OpenAlexW2792034535

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.