Evidence map›Paper›PMID 29495390›Full record

ArticleMolecules (Basel, Switzerland)2018

Aloin Suppresses Lipopolysaccharide-Induced Inflammatory Response and Apoptosis by Inhibiting the Activation of NF-κB.

Xuan Luo, Haowei Zhang, Xiduan Wei, Mengjuan Shi, Ping Fan, Weidong Xie, Yaou Zhang, Naihan Xu

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
5.7field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 52 citations in OpenAlex.

  1. Article
  2. Hormesis: induction byOpen medicine (Warsaw, Poland) · 2026
    Review
  3. Review
  4. Article
  5. Review
  6. Article
  7. Article
  8. Review
  9. Aloin Attenuates Oxidative Stress, Inflammation, and CClJournal of agricultural and food chemistry · 2023
    Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Immunoenhancing Effects ofMarine drugs · 2022
    Article
  16. Article
  17. Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Xuan LuoKey Lab in Healthy Science and Technology, Division of Life Science, Graduate School at Shenzhen, Tsinghua University, Shenzhen 518055, China. lxuan0721@163.com.
Haowei ZhangOpen FIESTA Center, Tsinghua University, Shenzhen 518055, China. zhwjack@hotmail.com.ORCID 0000-0003-4640-1005
Xiduan WeiKey Lab in Healthy Science and Technology, Division of Life Science, Graduate School at Shenzhen, Tsinghua University, Shenzhen 518055, China. weixiduan@126.com.
Mengjuan ShiKey Lab in Healthy Science and Technology, Division of Life Science, Graduate School at Shenzhen, Tsinghua University, Shenzhen 518055, China. 18700809087@163.com.
Ping FanKey Lab in Healthy Science and Technology, Division of Life Science, Graduate School at Shenzhen, Tsinghua University, Shenzhen 518055, China. pingf01@126.com.
Weidong XieKey Lab in Healthy Science and Technology, Division of Life Science, Graduate School at Shenzhen, Tsinghua University, Shenzhen 518055, China. xiewd@tsinghua.edu.cn.
Yaou ZhangKey Lab in Healthy Science and Technology, Division of Life Science, Graduate School at Shenzhen, Tsinghua University, Shenzhen 518055, China. zhangyo@sz.tsinghua.edu.cn.
Naihan XuKey Lab in Healthy Science and Technology, Division of Life Science, Graduate School at Shenzhen, Tsinghua University, Shenzhen 518055, China. xu.naihan@sz.tsinghua.edu.cn.
University Town of Shenzhen · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Numerous herbal-derived natural products are excellent anti-inflammatory agents. Several studies have reported that aloin, the major anthraquinone glycoside obtained from the

Indexed as

AnimalsAnti-Inflammatory AgentsApoptosisCell SurvivalCyclooxygenase 2CytokinesDisease Models, AnimalEmodinInflammationInflammation MediatorsLipopolysaccharidesMacrophagesMiceModels, BiologicalNF-kappa BNitric OxidealloinAnti-Inflammatory AgentsCyclooxygenase 2CytokinesEmodinInflammation MediatorsLipopolysaccharidesNF-kappa BNitric OxideNitric Oxide Synthase Type IITranscription Factor RelAaloinapoptosisinflammationmacrophagesNF-κB

Identifiers

PMID29495390
PMCPMC6017010
OpenAlexW2790444504

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.