Evidence map›Paper›PMID 29495330›Full record

ArticleNutrients2018

Serum Carotenoids Are Inversely Associated with RBP4 and Other Inflammatory Markers in Middle-Aged and Elderly Adults.

Lipeng Jing, Mianli Xiao, Hongli Dong, Jiesheng Lin, Gengdong Chen, Wenhua Ling, Yuming Chen

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 21 citations in OpenAlex.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Lipeng JingDepartment of Medical Statistics & Epidemiology, School of Public Health, Sun Yat-sen University, Guangzhou 510080, China. jinglp@mail2.sysu.edu.cn.
Mianli XiaoDepartment of Medical Statistics & Epidemiology, School of Public Health, Sun Yat-sen University, Guangzhou 510080, China. xiaomli@mail2.sysu.edu.cn.
Hongli DongDepartment of Medical Statistics & Epidemiology, School of Public Health, Sun Yat-sen University, Guangzhou 510080, China. dhljiyi@163.com.
Jiesheng LinDepartment of Medical Statistics & Epidemiology, School of Public Health, Sun Yat-sen University, Guangzhou 510080, China. linjsh6@mail2.sysu.edu.cn.
Gengdong ChenDepartment of Medical Statistics & Epidemiology, School of Public Health, Sun Yat-sen University, Guangzhou 510080, China. chgengd@163.com.
Wenhua LingGuangdong Provincial Key Laboratory of Food, Nutrition and Health, School of Public Health, Sun Yat-sen University, Guangzhou 510080, China. lingwh@mail.sysu.edu.cn.
Yuming ChenDepartment of Medical Statistics & Epidemiology, School of Public Health, Sun Yat-sen University, Guangzhou 510080, China. chenyum@mail.sysu.edu.cn.ORCID 0000-0003-1658-5528
Sun Yat-sen University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

(1) Background: Carotenoids may be inversely associated with inflammatory markers (i.e., TNF-α, IL-6, IL-1β). However, data are scarce on retinol binding protein 4 (RBP4) in humans. We examined the associations among serum carotenoids, RBP4 and several inflammatory markers in a Chinese population. (2) Methods: This community-based cross-sectional study included 3031 participants (68% males) aged 40-75 years in Guangzhou, China. Serum concentrations of carotenoids, RBP4, and inflammatory markers were measured. (3) Results: Generally, serum individual and total carotenoids were significantly and inversely associated with retinol-adjusted RBP4, RBP4, hsCRP, MCP1, and TNF-alpha levels. Age- and gender-adjusted partial correlation coefficients between total carotenoids and the above inflammatory markers were -0.129, -0.097, -0.159, -0.079, and -0.014 (all

Indexed as

AdultAgedBiomarkersCarotenoidsChemokine CCL2ChinaC-Reactive ProteinCross-Sectional StudiesFemaleHumansInflammationInterleukin-1betaInterleukin-6LuteinMaleMiddle AgedBiomarkersCarotenoidsCCL2 protein, humanChemokine CCL2C-Reactive ProteinIL1B protein, humanIL6 protein, humanInterleukin-1betaInterleukin-6LuteinRBP4 protein, humanRetinol-Binding Proteins, PlasmaTumor Necrosis Factor-alphaZeaxanthinsantioxidantcarotenoidsinflammatory markerretinol binding protein 4

Identifiers

PMID29495330
PMCPMC5872678
OpenAlexW2790790326

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.