Evidence map›Paper›PMID 29495105›Full record

ArticleJournal of thrombosis and haemostasis : JTH2018

The plasminogen receptor

L A Miles, N Baik, H Bai, H P Makarenkova, W B Kiosses, S Krajewski, F J Castellino, A Valenzuela, N M Varki, B M Mueller and 1 more

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of thrombosis and haemostasis : JTH, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.0field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Plg-RBiomolecules · 2022
    Article
  7. The plasminogen receptor Plg-RJournal of thrombosis and haemostasis : JTH · 2022
    Article
  8. Plasminogen Receptors and Fibrinolysis.International journal of molecular sciences · 2021
    Review
  9. The plasminogen receptor, Plg-RCell death & disease · 2020
    Article
  10. Article
  11. Functions of the plasminogen receptor Plg-RJournal of thrombosis and haemostasis : JTH · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 6 institutions in 1 country.

L A MilesDepartment of Molecular Medicine, The Scripps Research Institute, La Jolla, CA, USA.
N BaikDepartment of Molecular Medicine, The Scripps Research Institute, La Jolla, CA, USA.
H BaiVeterans Administration San Diego Healthcare System, San Diego, CA, USA.
H P MakarenkovaDepartment of Molecular Medicine, The Scripps Research Institute, La Jolla, CA, USA.
W B KiossesDepartment of Molecular Medicine, The Scripps Research Institute, La Jolla, CA, USA.
S KrajewskiSanford-Burnham Medical Research Institute, La Jolla, CA, USA.
F J CastellinoW.M. Keck Center for Transgene Research, University of Notre Dame, Notre Dame, IN, USA.
A ValenzuelaDepartment of Pathology, University of California San Diego, La Jolla, CA, USA.
N M VarkiDepartment of Pathology, University of California San Diego, La Jolla, CA, USA.
B M MuellerSan Diego Biomedical Research Institute, San Diego, CA, USA.
R J ParmerVeterans Administration San Diego Healthcare System, San Diego, CA, USA.
Scripps Research Institute · USUniversity of California, San Diego · USSan Diego Biomedical Research Institute · USSanford Burnham Prebys Medical Discovery Institute · USUniversity of Notre Dame · USVA San Diego Healthcare System · US

Funding

Siglec Modulation of Inflammatory ResponsesP01HL107150 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI VARKI, NISSI MARY · 2011 to 2017
$18.0M
Regulation of plasminogen-dependent cell functions by the novel receptor, Plg-RKTR01HL081046 · NHLBI · SCRIPPS RESEARCH INSTITUTE, THE · PI MILES, LINDSEY A · 2007 to 2024
$8.7M
STRUCTURE-FUNCTION STUDIES ON PLASMINOGEN AND PLASMINR01HL013423 · NHLBI · UNIVERSITY OF NOTRE DAME · PI CASTELLINO, FRANCIS J, LEE, SHAUN · 1985 to 2021
$7.9M
Lacrimal Gland Repair Using Progenitor CellsR01EY026202 · NEI · SCRIPPS RESEARCH INSTITUTE, THE · PI MAKARENKOVA, HELEN P. · 2016 to 2025
$5.2M
A Novel Plasminogen Receptor in Breast CancerR01CA166473 · NCI · TORREY PINES INST FOR MOLECULAR STUDIES · PI MILES, LINDSEY A, MUELLER, BARBARA MARIA · 2012 to 2016
$2.1M
Plasminogen and Plasmin: Structure and FunctionR56HL013423 · NHLBI · UNIVERSITY OF NOTRE DAME · PI CASTELLINO, FRANCIS J, LEE, SHAUN · 2022 to 2022
$743k
STRUCTURE/FUNCTION STUDIES ON PLASMINOGEN AND PLASMINR37HL013423 · NHLBI · UNIVERSITY OF NOTRE DAME · PI CASTELLINO, FRANCIS J · 1990 to 1999
–
Cell Surface Plasminogen Activation and HypertensionI01BX002026 · VA · VA SAN DIEGO HEALTHCARE SYSTEM · PI PARMER, ROBERT J · 2013 to 2016
–
BLRD VA I01 BX002026NCI NIH HHS R01 CA166473NEI NIH HHS R01 EY026202NHLBI NIH HHS P01 HL107150NHLBI NIH HHS R01 HL013423NHLBI NIH HHS R01 HL081046NHLBI NIH HHS R37 HL013423NHLBI NIH HHS R56 HL013423
6 · The paper itself

Abstract

Essentials Plg-R SUMMARY: Background Lactational competence requires plasminogen, the zymogen of the serine protease, plasmin. Plg-R

Indexed as

LactationMorphogenesisAnimalsApoptosisCell ProliferationExtracellular MatrixFemaleFibrinFibrinogenFibrosisGenotypeMacrophagesMammary Glands, AnimalMice, 129 StrainMice, Inbred C57BLMice, KnockoutFibrinFibrinogenPLG-R(KT) protein, mouseReceptors, Cell SurfacefibrinfibrinolysisplasminogenPLG-R(KT) protein, mousereceptors

Identifiers

PMID29495105
PMCPMC5965281
OpenAlexW2791528069

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.