ReviewCurrent opinion in microbiology2018
Microfluidics and single-cell microscopy to study stochastic processes in bacteria.
Review in Current opinion in microbiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
42 citing papers in PubMed.
- Differentiation between regulated and disrupted growth arrests allows tailoring of effective treatments for antibiotic persistence.Science advances · 2026Article
- Microfluidic point-of-care testing for antimicrobial resistance: advances, strategies, and One Health perspectives.Science in One Health · 2026Review
- Intracellular competition shapes plasmid population dynamics.Science (New York, N.Y.) · 2025Article
- Microbial single-cell applications under anoxic conditions.Applied and environmental microbiology · 2024Review
- Methods for studying microbial acid stress responses: from molecules to populations.FEMS microbiology reviews · 2024Review
- Scaling of stochastic growth and division dynamics: A comparative study of individual rod-shaped cells in the Mother Machine and SChemostat platforms.Molecular biology of the cell · 2024Article
- Article
- Microfluidic approaches in microbial ecology.Lab on a chip · 2024Review
- The protein carboxymethyltransferase-dependent aspartate salvage pathway plays a crucial role in the intricate metabolic network ofScience advances · 2024Article
- Tools and methods for high-throughput single-cell imaging with the mother machine.bioRxiv : the preprint server for biology · 2024Article
- Spatial exclusion leads to "tug-of-war" ecological dynamics between competing species within microchannels.PLoS computational biology · 2023Article
- Recent Advances in Bacterial Persistence Mechanisms.International journal of molecular sciences · 2023Review
- Out-of-equilibrium gene expression fluctuations in the presence of extrinsic noise.Physical biology · 2023Article
- Quantifying stochastic establishment of mutants in microbial adaptation.Microbiology (Reading, England) · 2023Review
- The Quantification of Bacterial Cell Size: Discrepancies Arise from Varied Quantification Methods.Life (Basel, Switzerland) · 2023Article
- High-Efficiency Single-Cell Containment Microdevices Based on Fluid Control.Micromachines · 2023Article
- Changes in interactions over ecological time scales influence single-cell growth dynamics in a metabolically coupled marine microbial community.The ISME journal · 2023Article
- Navigating Environmental Transitions: the Role of Phenotypic Variation in Bacterial Responses.mBio · 2022Review
- rRNA operon multiplicity as a bacterial genome stability insurance policy.Nucleic acids research · 2022Article
- Microfluidic dose-response platform to track the dynamics of drug response in single mycobacterial cells.Scientific reports · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
Bacteria have molecules present in low and fluctuating numbers that randomize cell behaviors. Understanding these stochastic processes and their impact on cells has, until recently, been limited by the lack of single-cell measurement methods. Here, we review recent developments in microfluidics that enable following individual cells over long periods of time under precisely controlled conditions, and counting individual fluorescent molecules in many cells. We showcase discoveries that were made possible using these devices in various aspects of microbiology, such as antibiotic tolerance/persistence, cell-size control, cell-fate determination, DNA damage response, and synthetic biology.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.