ArticlePloS one2018
Comprehensive transcriptome analysis and flavonoid profiling of Ginkgo leaves reveals flavonoid content alterations in day-night cycles.
Article in PloS one, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed.
- Progressive salinity drives flavonoid branch reprogramming in Anoectochilus roxburghii.BMC plant biology · 2026Article
- A Comprehensive Analysis of Transcriptomics and Metabolomics Reveals Key Genes Involved in Terpenes Biosynthesis Pathway ofInternational journal of molecular sciences · 2025Article
- Identification of a central regulator of ginkgolide biosynthesis inProceedings of the National Academy of Sciences of the United States of America · 2025Article
- Comparative transcriptome analyses of different orthosiphon aristatus tissues reveal differentially expressed genes associated with flavonoid biosynthesis.Scientific reports · 2025Article
- Overexpression of thePlant signaling & behavior · 2023Article
- Modulation of defense genes and phenolic compounds in wild blueberry in response to Botrytis cinerea under field conditions.BMC plant biology · 2023Article
- Analysis of Camellia oleifera transcriptome reveals key pathways and hub genes involved during different photoperiods.BMC plant biology · 2022Article
- High-Depth Transcriptome Reveals Differences in Natural HaploidInternational journal of molecular sciences · 2022Article
- Regulation mechanisms of flavonoids biosynthesis of Hancheng Dahongpao peels (Zanthoxylum bungeanum Maxim) at different development stages by integrated metabolomics and transcriptomics analysis.BMC plant biology · 2022Article
- Plant circadian clock control of Medicago truncatula nodulation via regulation of nodule cysteine-rich peptides.Journal of experimental botany · 2022Article
- Flavonoid Synthesis and Metabolism During the Fruit Development in Hickory (Frontiers in plant science · 2022Article
- Transgenic tobacco plant overexpressing ginkgo dihydroflavonol 4-reductase geneFrontiers in plant science · 2022Article
- Molecular cloning and expression analysis of a WRKY transcription factor gene,Plant signaling & behavior · 2021Article
- LED Lights Promote Growth and Flavonoid Accumulation ofPlants (Basel, Switzerland) · 2020Article
- Root-knot nematodes demonstrate temporal variation in host penetration.Journal of nematology · 2020Article
- Article
- A semi-dominant mutation in a CC-NB-LRR-type protein leads to a short-root phenotype in rice.Rice (New York, N.Y.) · 2018Article
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7 authors.
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Abstract
Ginkgo leaves are raw materials for flavonoid extraction. Thus, the timing of their harvest is important to optimize the extraction efficiency, which benefits the pharmaceutical industry. In this research, we compared the transcriptomes of Ginkgo leaves harvested at midday and midnight. The differentially expressed genes with the highest probabilities in each step of flavonoid biosynthesis were down-regulated at midnight. Furthermore, real-time PCR corroborated the transcriptome results, indicating the decrease in flavonoid biosynthesis at midnight. The flavonoid profiles of Ginkgo leaves harvested at midday and midnight were compared, and the total flavonoid content decreased at midnight. A detailed analysis of individual flavonoids showed that most of their contents were decreased by various degrees. Our results indicated that circadian rhythms affected the flavonoid contents in Ginkgo leaves, which provides valuable information for optimizing their harvesting times to benefit the pharmaceutical industry.
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