Evidence map›Paper›PMID 29494521›Full record

ArticleInternational journal of molecular sciences2018

Influence of Single-Nucleotide Polymorphisms in PPAR-δ, PPAR-γ, and PRKAA2 on the Changes in Anthropometric Indices and Blood Measurements through Exercise-Centered Lifestyle Intervention in Japanese Middle-Aged Men.

Yuichiro Nishida, Minako Iyadomi, Hirotaka Tominaga, Hiroaki Taniguchi, Yasuki Higaki, Hiroaki Tanaka, Mikako Horita, Chisato Shimanoe, Megumi Hara, Keitaro Tanaka

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.4field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 2 countries.

Yuichiro NishidaDepartment of Preventive Medicine, Faculty of Medicine, Saga University, Saga 849-8501, Japan. ynishida@cc.saga-u.ac.jp.ORCID 0000-0003-2320-7234
Minako IyadomiSUMCO Corporation, Saga 849-4271, Japan. miyadomi@sumcosi.com.
Hirotaka TominagaSection of Clinical Cooperation System, Center for Comprehensive Community Medicine, Faculty of Medicine, Saga University, Saga 849-8501, Japan. hirotaka@cc.saga-u.ac.jp.ORCID 0000-0002-7234-5708
Hiroaki TaniguchiInstitute of Genetics and Animal Breeding of the Polish Academy of Sciences, 05-552 Jastrzebiec, Poland. h.taniguchi@ighz.pl.
Yasuki HigakiLaboratory of Exercise Physiology, Faculty of Health and Sports Science, Fukuoka University, Fukuoka 814-0180, Japan. higaki@fukuoka-u.ac.jp.
Hiroaki TanakaLaboratory of Exercise Physiology, Faculty of Health and Sports Science, Fukuoka University, Fukuoka 814-0180, Japan. htanaka@fukuoka-u.ac.jp.
Mikako HoritaDepartment of Preventive Medicine, Faculty of Medicine, Saga University, Saga 849-8501, Japan. horitam@cc.saga-u.ac.jp
Chisato ShimanoeDepartment of Preventive Medicine, Faculty of Medicine, Saga University, Saga 849-8501, Japan. chisatos@cc.saga-u.ac.jp.ORCID 0000-0002-3561-9538
Megumi HaraDepartment of Preventive Medicine, Faculty of Medicine, Saga University, Saga 849-8501, Japan. harameg@cc.saga-u.ac.jp.ORCID 0000-0002-8708-3237
Keitaro TanakaDepartment of Preventive Medicine, Faculty of Medicine, Saga University, Saga 849-8501, Japan. tanakake@cc.saga-u.ac.jp.
Saga University · JPFukuoka University · JPPolish Academy of Sciences · PLSumco Corporation (Japan) · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The purpose of the current study was to examine the influence of single-nucleotide polymorphisms (SNPs) in the peroxisome proliferator-activated receptor-δ (PPAR-δ), PPAR-γ, and α2 isoforms of the catalytic subunit of AMP-activated protein kinase (PRKAA2) on the extent of changes in anthropometric indices and blood measurements through exercise-centered lifestyle intervention in middle-aged men. A total of 109 Japanese middle-aged male subjects (47.0 ± 0.4 years) participated in the baseline health checkup, 6-month exercise-centered lifestyle intervention, and second checkup conducted several months after the subject completed the intervention. The body mass index (BMI), waist circumference, and clinical measurements, including hemoglobin A

Indexed as

AnthropometryLife StylePolymorphism, Single NucleotideAge FactorsAllelesAMP-Activated Protein KinasesBiomarkersExerciseGene FrequencyGenetic Predisposition to DiseaseGenotypeHumansJapanMaleMiddle AgedObesityAMP-Activated Protein KinasesBiomarkersPPAR deltaPPAR gammaPRKAA2 protein, humanexerciseglucoseHbA1clipidliver enzymeobesityPPARSNP

Identifiers

PMID29494521
PMCPMC5877564
OpenAlexW2790498281

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.