Evidence map›Paper›PMID 29494424›Full record

Trial reportAIDS (London, England)2018

Effect of HIV self-testing on the number of sexual partners among female sex workers in Zambia.

Catherine E Oldenburg, Michael M Chanda, Katrina F Ortblad, Magdalene Mwale, Steven Chongo, Nyambe Kamungoma, Catherine Kanchele, Andrew Fullem, Caitlin Moe, Leah G Barresi and 2 more

Registry-linked trialAbstract readRandomized Controlled Trial
In one paragraph

Trial report in AIDS (London, England), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02827240 (A Peer Educator-delivered HIV Self-testing Intervention for Female Sex Workers in Zambian Border Towns), which is not on this map. Cited by 18 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02827240 nacompletednot on this map

A Peer Educator-delivered HIV Self-testing Intervention for Female Sex Workers in Zambian Border Towns

TypeinterventionalSponsorHarvard School of Public Health (HSPH)Ran2016 to 2017Enrolled965ConditionsHIV InfectionArmsOral HIV Self-Testing
3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 3 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Catherine E OldenburgFrancis I. Proctor Foundation.
Michael M ChandaJohn Snow, Inc., Lusaka, Zambia.
Katrina F OrtbladDepartment of Global Health and Population, Harvard T.H. Chan School of Public Health.
Magdalene MwaleJohn Snow, Inc., Lusaka, Zambia.
Steven ChongoJohn Snow, Inc., Lusaka, Zambia.
Nyambe KamungomaJohn Snow, Inc., Lusaka, Zambia.
Catherine KancheleJohn Snow, Inc., Lusaka, Zambia.
Andrew FullemJohn Snow, Inc., Boston.
Caitlin MoeFrancis I. Proctor Foundation.
Leah G BarresiDepartment of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA.
Guy D HarlingDepartment of Global Health and Population, Harvard T.H. Chan School of Public Health.
Till BärnighausenDepartment of Global Health and Population, Harvard T.H. Chan School of Public Health.

Funding

HIV and Other Infectious Consequences of Substance UseT32DA013911 · NIDA · MIRIAM HOSPITAL · PI TRACI C GREEN, JOSIAH D RICH · 2001 to 2026
$9.6M
Epidemiology of Infectious Diseases and BiodefenseT32AI007535 · NIAID · HARVARD UNIVERSITY (SCH OF PUBLIC HLTH) · PI GRAD, YONATAN H, MURRAY, MEGAN B · 1998 to 2025
$4.8M
The Brown Initiative in HIV and AIDS Clinical Research for Minority CommunitiesR25MH083620 · NIMH · MIRIAM HOSPITAL · PI NUNN, AMY STEWART · 2008 to 2025
$3.7M
NIAID NIH HHS T32 A1007535NIAID NIH HHS T32 AI007535NIDA NIH HHS T32 DA013911NIMH NIH HHS R25 MH083620
6 · The paper itself

Abstract

objectivesTo assess the effect of two health system approaches to distribute HIV self-tests on the number of female sex workers' client and nonclient sexual partners.

designCluster randomized controlled trial.

methodsPeer educators recruited 965 participants. Peer educator-participant groups were randomized 1 : 1 : 1 to one of three arms: delivery of HIV self-tests directly from a peer educator, free facility-based delivery of HIV self-tests in exchange for coupons, or referral to standard-of-care HIV testing. Participants in all three arms completed four peer educator intervention sessions, which included counseling and condom distribution. Participants were asked the average number of client partners they had per night at baseline, 1 and 4 months, and the number of nonclient partners they had in the past 12 months (at baseline) and in the past month (at 1 month and 4 months).

resultsAt 4 months, participants reported significantly fewer clients per night in the direct delivery arm (mean difference -0.78 clients, 95% CI -1.28 to -0.28, P = 0.002) and the coupon arm (-0.71, 95% CI -1.21 to -0.21, P = 0.005) compared with standard of care. Similarly, they reported fewer nonclient partners in the direct delivery arm (-3.19, 95% CI -5.18 to -1.21, P = 0.002) and in the coupon arm (-1.84, 95% CI -3.81 to 0.14, P = 0.07) arm compared with standard of care.

conclusionExpansion of HIV self-testing may have positive behavioral effects enhancing other HIV prevention efforts among female sex workers in Zambia.

trial registrationClinicalTrials.gov NCT02827240.

Indexed as

Self AdministrationSexual BehaviorSex WorkersAdultDiagnostic Tests, RoutineFemaleHIV InfectionsHumansYoung AdultZambia

Identifiers

PMID29494424
PMCPMC5844591

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.