Evidence map›Paper›PMID 29494182›Full record

ArticlePsychology and aging2018

Association between subjective memory assessment and associative memory performance: Role of ad risk factors.

Marci M Horn, Kristen M Kennedy, Karen M Rodrigue

Open access · hybridAbstract read
In one paragraph

Article in Psychology and aging, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it, 30 citations in OpenAlex.

  1. Pooled it
  2. The physiological effects of APOE genotype in healthy young/middle-aged individuals.Biological reviews of the Cambridge Philosophical Society · 2026
    Article
  3. Article
  4. Early midlife ovarian removal is associated with lower posterior hippocampal function.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025
    Article
  5. Article
  6. Article
  7. Article
  8. Age Deficits in Associative Memory Are Not Alleviated by Multisensory Paradigms.The journals of gerontology. Series B, Psychological sciences and social sciences · 2024
    Article
  9. Evidence for the role of affective theory of mind in face-name associative memory.Neuropsychology, development, and cognition. Section B, Aging, neuropsychology and cognition · 2024
    Article
  10. Article
  11. Article
  12. Article
  13. Article
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  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Marci M HornCenter for Vital Longevity, School of Behavioral and Brain Sciences, The University of Texas at Dallas.
Kristen M KennedyCenter for Vital Longevity, School of Behavioral and Brain Sciences, The University of Texas at Dallas.
Karen M RodrigueCenter for Vital Longevity, School of Behavioral and Brain Sciences, The University of Texas at Dallas.ORCID 0000-0002-4781-7961
The University of Texas at Dallas · US

Funding

Dopaminergic and Neuroplastic Influences on Longitudinal Change in Cognitive and Brain AgingR01AG056535 · NIA · UNIVERSITY OF TEXAS DALLAS · PI Kristen M. Kennedy, Karen M Rodrigue · 2017 to 2026
$4.8M
Role of White Matter Integrity in Age-Related Functional ReorganizationR00AG036818 · NIA · UNIVERSITY OF TEXAS DALLAS · PI KENNEDY, KRISTEN M. · 2012 to 2014
$733k
Vascular Effects on Normal Neural and Cognitive AgingR00AG036848 · NIA · UNIVERSITY OF TEXAS DALLAS · PI RODRIGUE, KAREN M · 2012 to 2014
$733k
Lilly Pharmaceuticals; Avid RadiopharmaceuticalsNIA NIH HHS R00 AG036818NIA NIH HHS R00 AG036848NIA NIH HHS R01 AG056535NIH HHS
6 · The paper itself

Abstract

Decline in associative memory abilities is a common cognitive complaint among older adults and is detectable in both normal aging and in prodromal Alzheimer's disease (AD). Subjective memory (SM) complaints may serve as an earlier marker of these mnemonic changes; however, previous research examining the predictive utility of SM to observed memory performance yielded inconsistent results. This inconsistency is likely due to other sources of variance that occur with memory decline such as mood/depression issues, presence of apolipoprotein E (APOE ε4) genotype, or beta-amyloid deposition. Here we examine the relationship between SM and associative memory ability in the context of factors that increase susceptibility to AD in 195 healthy adults (79 men) aged 20-94 years. Participants completed an SM questionnaire, a mood/depression scale, two associative memory tests (a word-pair and a name-face test), and were genotyped for APOE ε4. PET-amyloid imaging data were collected for a subset of those over 50 years of age (N = 74). We found that SM predicted performance on both associative memory tests even after covarying for age, sex, mood, and APOE ε4 status. Interestingly, for the name-face associative task, increased SM concerns predicted memory performance selectively in participants over the age of 60, with the APOEε4 risk group showing the strongest effect. Finally, men with higher beta-amyloid deposition reported more memory complaints. Our findings suggest that SM reliably tracks memory performance, even in cognitively healthy adults, and may reflect an increased risk for AD. (PsycINFO Database Record

Indexed as

MemoryAdultAgedAged, 80 and overAgingApolipoproteins EFemaleHumansMaleMiddle AgedRisk FactorsYoung AdultApolipoproteins E

Identifiers

PMID29494182
PMCPMC5836750
OpenAlexW2792211318

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.