ReviewMagnetic resonance in medicine2018
On modeling.
Review in Magnetic resonance in medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 199 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
199 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Variability by region and method in human brain sodium concentrations estimated byScientific reports · 2023Pooled it
- Imaging Alzheimer's genetic risk using diffusion MRI: A systematic review.NeuroImage. Clinical · 2020Pooled it
- Arachidonic and docosahexaenoic acid supplementation affects white matter microstructure in preterm infants.Brain communications · 2026Trial
- Comparison of multi echo TScientific reports · 2021Trial
- Comparative Systematic Analysis of Gray Matter Biophysical Models on a Public Dataset.Magnetic resonance in medicine · 2026Article
- Electroconvulsive therapy modulates neurite density and free water in discrete white matter compartments in major depression.Research square · 2026Article
- Gray Matter Microstructure Measured Using Diffusion Imaging as a Biomarker of Severity in Lewy Body Diseases.Movement disorders : official journal of the Movement Disorder Society · 2026Article
- Restriction-Weighted Q-Space Trajectory Imaging (ResQ): Toward Mapping Diffusion-Time Effects With Tensor-Valued Diffusion Encoding in Human Prostate Cancer Xenografts.NMR in biomedicine · 2026Article
- Microstructure imaging of prostate cancer by diffusion MRI.Magma (New York, N.Y.) · 2026Review
- The role of diffusion-weighted MRI in biological image-guided radiation therapy: a roadmap.Physics in medicine and biology · 2026Review
- The MRI two-perfusion IVIM model improves understanding of SARS-CoV-2 virus impact on placental tissue.Magma (New York, N.Y.) · 2026Article
- Informed Dictionary-Guided Monte Carlo Inversion for Robust and Reproducible Multidimensional MRI.Magnetic resonance in medicine · 2026Article
- What If Each Voxel Were Measured With a Different Diffusion Protocol?Magnetic resonance in medicine · 2026Article
- Multi-modal Monte Carlo MRI simulator of tissue microstructure.Imaging neuroscience (Cambridge, Mass.) · 2026Article
- Sampling of non-Gaussian Ensemble Average Propagators for the simulation of diffusion magnetic resonance images.Magnetic resonance in medicine · 2026Article
- Ultra-high gradient connectomics and microstructure MRI scanner for imaging of human brain circuits across scales.Nature biomedical engineering · 2026Article
- On the structural and practical identifiability of multi-echo BBB-ASL tracer kinetic models.Magnetic resonance in medicine · 2026Article
- Thermal noise lowers the accuracy of rotationally invariant harmonics of diffusion MRI data and their robustness to experimental variations.Magnetic resonance in medicine · 2026Article
- Data-driven classification of tissue water populations by massively multidimensional diffusion-relaxation correlation MRI.Frontiers in neuroscience · 2026Article
- Validating the standard model of diffusion MRI in white matter with numerical substrates.Imaging neuroscience (Cambridge, Mass.) · 2026Article
139 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
Mapping tissue microstructure with MRI holds great promise as a noninvasive window into tissue organization at the cellular level. Having originated within the realm of diffusion NMR in the late 1970s, this field is experiencing an exponential growth in the number of publications. At the same time, model-based approaches are also increasingly incorporated into advanced MRI acquisition and reconstruction techniques. However, after about two decades of intellectual and financial investment, microstructural mapping has yet to find a single commonly accepted clinical application. Here, we suggest that slow progress in clinical translation may signify unresolved fundamental problems. We outline such problems and related practical pitfalls, as well as review strategies for developing and validating tissue microstructure models, to provoke a discussion on how to bridge the gap between our scientific aspirations and the clinical reality. We argue for recalibrating the efforts of our community toward a more systematic focus on fundamental research aimed at identifying relevant degrees of freedom affecting the measured MR signal. Such a focus is essential for realizing the truly revolutionary potential of noninvasive three-dimensional in vivo microstructural mapping.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.