Evidence map›Paper›PMID 29493404›Full record

ReviewThe veterinary quarterly2018

Mycobacterium marinum infection in fish and man: epidemiology, pathophysiology and management; a review.

Emad Hashish, Abdallah Merwad, Shimaa Elgaml, Ali Amer, Huda Kamal, Ahmed Elsadek, Ayman Marei, Mahmoud Sitohy

Open access · goldAbstract readReview
In one paragraph

Review in The veterinary quarterly, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 93 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
93citing papers in PubMed, 2 pooled it
8.4field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

93 citing papers in PubMed, 2 syntheses or guidelines pooled it, 196 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Infectious disease reports · 2026
    Article
  4. Pathogens (Basel, Switzerland) · 2026
    Article
  5. Review
  6. TiOInternational journal of molecular sciences · 2026
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. International medical case reports journal · 2026
    Article
  13. Article
  14. Article
  15. Atypical waves: nonsporotrichoidSkin health and disease · 2025
    Article
  16. Outbreak of 32Emerging microbes & infections · 2025
    Article
  17. Article
  18. Article
  19. Pathogenesis of Cutaneous Mycobacterial Infections-International journal of molecular sciences · 2025
    Review
  20. Pathogens (Basel, Switzerland) · 2025
    Review

33 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Emad Hashisha Department of Clinical Pathology, Faculty of Veterinary Medicine , Zagazig University , Egypt.
Abdallah Merwadb Department of Zoonoses, Faculty of Veterinary Medicine , Zagazig University , Egypt.
Shimaa Elgamla Department of Clinical Pathology, Faculty of Veterinary Medicine , Zagazig University , Egypt.
Ali Amerc Tuberculosis Unit , Animal Health Research Institute (AHRI) , Giza , Egypt.
Huda Kamald Department of Meat Hygiene , National Research Center (NRC) , Zagazig , Egypt.
Ahmed Elsadeke Immunology Research Lab, Immunology Division, Department of Microbiology and Immunology, Faculty of Medicine , Zagazig University , Egypt.
Ayman Mareie Immunology Research Lab, Immunology Division, Department of Microbiology and Immunology, Faculty of Medicine , Zagazig University , Egypt.
Mahmoud Sitohyf Department of Biochemistry, Faculty of Agriculture , Zagazig University , Egypt.
Zagazig University · EGHousing and Building National Research Center · EG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mycobacterium marinum is an opportunistic pathogen inducing infection in fresh and marine water fish. This pathogen causes necrotizing granuloma like tuberculosis, morbidity and mortality in fish. The cell wall-associated lipid phthiocerol dimycocerosates, phenolic glycolipids and ESAT-6 secretion system 1 (ESX-1) are the conserved virulence determinant of the organism. Human infections with Mycobacterium marinum hypothetically are classified into four clinical categories (type I-type IV) and have been associated with the exposure of damaged skin to polluted water from fish pools or contacting objects contaminated with infected fish. Fish mycobacteriosis is clinically manifested and characterized in man by purple painless nodules, liable to develop into superficial crusting ulceration with scar formation. Early laboratory diagnosis of M. marinum including histopathology, culture and PCR is essential and critical as the clinical response to antibiotics requires months to be attained. The pathogenicity and virulence determinants of M. marinum need to be thoroughly and comprehensively investigated and understood. In spite of accumulating information on this pathogen, the different relevant data should be compared, connected and globally compiled. This article is reviewing the epidemiology, virulence factors, diagnosis and disease management in fish while casting light on the potential associated public health hazards.

Indexed as

Mycobacterium Infections, NontuberculousAnimalsFish DiseasesFishesHumansMycobacterium marinumWater MicrobiologyZoonosesepidemiologyFishMycobacterium marinumpathophysiologypublic healthvirulence factors

Identifiers

PMID29493404
PMCPMC6831007
OpenAlexW2792569056

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.