Evidence map›Paper›PMID 29493107›Full record

ArticlePediatric obesity2018

The positive association of infant weight gain with adulthood body mass index has strengthened over time in the Fels Longitudinal Study.

K Lucas, P James, A C Choh, M Lee, S A Czerwinski, E W Demerath, W Johnson

Abstract read
In one paragraph

Article in Pediatric obesity, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

K LucasDepartment of Population Health, London School of Hygiene and Tropical Medicine, London, UK.
P JamesMRC Unit, The Gambia and MRC International Nutrition Group, London School of Hygiene and Tropical Medicine, London, UK.
A C ChohDepartment of Epidemiology, Human Genetics and Environmental Sciences, The University of Texas Health Science Center at Houston, School of Public Health, Houston, USA.
M LeeDepartment of Epidemiology, Human Genetics and Environmental Sciences, The University of Texas Health Science Center at Houston, School of Public Health, Houston, USA.
S A CzerwinskiDepartment of Epidemiology, Human Genetics and Environmental Sciences, The University of Texas Health Science Center at Houston, School of Public Health, Houston, USA.
E W DemerathDivision of Epidemiology and Community Health, School of Public Health, University of Minnesota, Minneapolis, USA.
W JohnsonSchool of Sport, Exercise and Health Sciences, Loughborough University, Loughborough, UK.ORCID 0000-0002-0347-4354

Funding

SUBCUTANEOUS FAT, BLOOD LIPIDS AND SUBSEQUENT OUTCOMER01HD012252 · NICHD · WRIGHT STATE UNIVERSITY · PI CZERWINSKI, STEFAN A. · 1985 to 2014
$17.3M
Medical Research Council MR/P023347/1NICHD NIH HHS R01 HD012252
6 · The paper itself

Abstract

backgroundInfant weight gain is positively related to adulthood body mass index (BMI), but it is unknown whether or not this association is stronger for individuals born during (compared with before) the obesity epidemic.

objectivesThe aim of the study was to examine how the infant weight gain-adulthood BMI association might have changed across successive birth year cohorts spanning most of the 20th century.

methodsThe sample comprised 346 participants in the Fels Longitudinal Study. Confounder-adjusted regression models were used to test the associations of conditional weight-for-length Z-score, capturing weight change between ages 0-2 years, with young adulthood BMI and blood pressure, including cohort [1933-1949 {N = 137}, 1950-1969 {N = 108}, 1970-1997 {N = 101}] as an effect modifier.

resultsConditional weight-for-length Z-score was positively related to adulthood BMI, but there was significant effect modification by birth year cohort such that the association was over two times stronger in the 1970-1997 cohort (β 2.31; 95% confidence interval 1.59, 3.03) compared with the 1933-1949 (0.98; 0.31, 1.65) and 1950-1969 (0.87; 0.21, 1.54) cohorts. A similar pattern was found for systolic blood pressure.

conclusionsThe infant weight gain-adulthood BMI association was over two times stronger among a cohort born during the obesity epidemic era compared with cohorts born earlier in the 20th century.

Indexed as

Body Mass IndexAdolescentAdultAge FactorsAgingBirth WeightBlood PressureBody WeightChild, PreschoolCohort StudiesFemaleHumansInfantInfant, NewbornLongitudinal StudiesMaleAdulthood body mass indexbirth cohort studyinfant weight gainsecular trend

Identifiers

PMID29493107
PMCPMC8782254

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.